تحضير و تشخيص بعض قواعد شيف المحضرة من صبغة الأكرافلافين

Abstract EN

This research involved the preparation of Acrilflavin derivatives were characterized, which starting with Schiff bases , which are synthesized by condensation of Acrilflavin with 2-mole from of benzyldehyde ,N,N-dimethyl amine benzyldehyde, O-methoxy benzyldehyde ,benzoin, p-Nitro benzyldehyde , P-hydroxy benzyldehyde , O-Bromo benzyldehyde to give the following compounds, 1-N3,N6-dibenzylidene-10-methyl-4a,10-dihydroacridine-3,6-diamine.,2-(N3E,N6E)-N3,N6-bis(4-(dimethylamino)benzylidene)-10-methyl-4a,10-dihydroacridine-3,6-diamine.3-(N3E,N6E)-N3,N6-bis(2-methoxybenzylidene)-10-methyl-4a,10-dihydroacridine-3,6-diamine.4-(2Z,2'E)-2,2'-(10-methyl-4a,10-dihydroacridine-3,6-diyl)bis(azan-1-yl-1-ylidene)bis(1,2-diphenylethanol).5-(N3E,N6E)-10-methyl-N3,N6-bis(4-nitrobenzylidene)-4a,10-dihydroacridine-3,6-diamine.6-(N3E,N6E)-N3,N6-bis(2-bromobenzylidene)-10-methyl-4a,10-dihydroacridine-3,6-diamine.7-4,47 7 7 -(E,l'E)-(10-methyl-4a,10-dihydroacridine-3,6-diyl)bis(azan-l-yl-1-ylidene)bis(methan-1-yl-1-ylidene)diphenol.The reaction undergoes in acid medium by using Catalyst acetic acid.

These derivatives were identified by their m.ps, elemental analysis(C.H.N),IR spectra.The derivatives have long been known to possess hypnotics activity and it is may be to get hypnotics activity from the newly prepared compounds.