Mortality and morbidity in HFrEF, HFmrEF, and HFpEF patients with diabetes in the Middle East
Joint Authors
Sulaiman, Kazim
al-Mutarib, Ahmad
Rajan, Rajesh
Dashti, Raja
Bulbanat, Bassam
al-Suwayyid, Jasim
Bazargani, Nooshin
Panduranga, Prashanth
al-Jar Allah, Muhammad
al-Zakwani, Ibrahim
Ridha, Mustafa
Amin, Haitham
Asaad, Nidal
al-Falih, Husam
al-Mahmid, Wail
al-Asfar, Abd al-Fatah A.
al-Habib, Khalid F.
Source
Issue
Vol. 35, Issue 1 (31 Jan. 2020)8 p.
Publisher
Publication Date
2020-01-31
Country of Publication
Oman
No. of Pages
8
Main Subjects
Abstract EN
We sought to estimate the mortality and morbidity in diabetic acute heart failure (AHF) patients stratified by left ventricular ejection fraction.
Methods: We analyzed the data of patients with AHF from seven Middle Eastern countries (Bahrain, Oman, Yemen, Kuwait, UAE, Qatar, and Saudi Arabia) from February to November 2012, who were enrolled in a multinational registry of patients with heart failure (HF).
Results: A total of 2258 AHF patients had diabetes mellitus.
The mean age was 63.0±11.0 years (ranging from 18 to 99 years), and 60.3% (n = 1362) of the patients were males.
The mean ejection fraction (EF) was 37.0±13.0%.
HF with reduced EF (< 40%) (HFrEF) was observed in 1268 patients (56.2%), whereas 515 patients (22.8%) had mid-range (40–49%) (HFmrEF) and 475 patients (21.0%) had preserved EF (≥ 50%) (HFpEF).
The overall cumulative all-cause mortalities at three- and 12-months follow-up were 11.8% (n = 266) and 20.7% (n = 467), respectively.
Those with HFpEF were associated with lower three-months cumulative all-cause mortality compared to those with HFrEF (7.6% vs.
5.9%; adjusted odds ratio (aOR) = 0.54, 95% confidence interval (CI): 0.31–0.95; p = 0.031), but not significantly different when compared to those with HFmrEF (aOR = 0.86, 95% CI: 0.53–1.40; p = 0.554).
There were largely no significant differences among the groups with regards to the 12-months all-cause cumulative mortality (11% vs.
11% vs.
10%; p = 0.984).
There were also no significant differences in re-hospitalization rates between the three HF groups not only at three months (23% vs.
20% vs.
22%; p = 0.520), but at one-year follow-up (28% vs.
30% vs.
32%; p = 0.335).
Conclusions: Three-month cumulative all-cause mortality was high in diabetic HFrEF patients when compared to those with HFpEF.
However, there were no significant differences in mortality at one-year follow-up between the HF groups.
There were also no significant differences in re-hospitalization rates between the HF groups not only at three months but also at one-year follow-up in the Middle East.
American Psychological Association (APA)
al-Jar Allah, Muhammad& Rajan, Rajesh& al-Zakwani, Ibrahim& Dashti, Raja& Bulbanat, Bassam& al-Shaykh Ali, Alawi A.…[et al.]. 2020. Mortality and morbidity in HFrEF, HFmrEF, and HFpEF patients with diabetes in the Middle East. Oman Medical Journal،Vol. 35, no. 1.
https://search.emarefa.net/detail/BIM-955467
Modern Language Association (MLA)
al-Shaykh Ali, Alawi A.…[et al.]. Mortality and morbidity in HFrEF, HFmrEF, and HFpEF patients with diabetes in the Middle East. Oman Medical Journal Vol. 35, no. 1 (Jan. 2020).
https://search.emarefa.net/detail/BIM-955467
American Medical Association (AMA)
al-Jar Allah, Muhammad& Rajan, Rajesh& al-Zakwani, Ibrahim& Dashti, Raja& Bulbanat, Bassam& al-Shaykh Ali, Alawi A.…[et al.]. Mortality and morbidity in HFrEF, HFmrEF, and HFpEF patients with diabetes in the Middle East. Oman Medical Journal. 2020. Vol. 35, no. 1.
https://search.emarefa.net/detail/BIM-955467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-955467