Comparing the activity of some local and commercial antibiotics

Abstract EN

A comparison has been performed between 5 local antibiotics and 5 commercially imported antibiotics of the same kind: Ampicillin, Amoxicillin, Cefotaxime, Tetracycline, and Clarithromycin, in an aim to compare the efficiency of local and commercial antibiotics.

Bacterial sensitivity against these antibiotics was detected.

Disk diffusion method and Minimal Inhibitory Concentration (MIC) was used to detect antimicrobial sensitivity.

Results showed an increase in the inhibition zone of local antibiotics in general compared to commercial antibiotics , especially for Cefotaxime which showed significant increase in the inhibition zone of the local product compared to the commercial product against Staphylococcus aureus (23mm vs.

17mm) and Pseudomonas aerugenosa (17mm vs.7mm), both at (P<0.05).

Similarly, Tetracycline against Klebsiella spp (32mm vs.

26mm) and Clarithromycin against Proteus mirabilis (11mm vs.

7mm).The MIC test showed parallel results with the disk diffusion method.

In conclusion, local antibiotics have good activity and must be encouraged and supported rather than commercial antibiotics.