Vitamin B12 deficiency in diabetic patients on metformin therapy : a cross-sectional study from Oman

Other Title(s)

نقص فيتامين B12 لدى مرضى السكري على علاج الميتفورمين : دراسة مستعرضة من عمان

Joint Authors

Jaju, Sanjay
Al-Gahhafi, Muhammad
al-Rushdi, Shihab
al-Mamari, Ali
al-Mahrezi, Abd al-Aziz
al-Hamdi, Ahmad A.

Source

Sultan Qaboos University Medical Journal

Issue

Vol. 20, Issue 1 (29 Feb. 2020), pp.90-94, 5 p.

Publisher

Sultan Qaboos University College of Medicine and Health Sciences

Publication Date

2020-02-29

Country of Publication

Oman

No. of Pages

5

Main Topic

Diseases

Topics

Abstract EN

Objectives: This study aimed to determine the prevalence of vitamin B12 deficiency amongst diabetic patients on metformin therapy.

Methods: This cross-sectional study was conducted at general clinics at the University Health Center and diabetes outpatient clinics at Sultan Qaboos University Hospital, Muscat, Oman, between January and December 2017.

All Omani adults who were diagnosed with type 2 diabetes mellitus and took metformin were invited to participate in the study.

The variables included in this study were age, gender, duration of diabetes, dose and duration of metformin therapy, haemoglobin and glycosylated haemoglobin level.

Results: A total of 248 subjects were included (response rate = 95.4%) of which 26 (10.5%) were vitamin B12 deficient and 53 (21.4%) were borderline deficient.

The mean daily dose of metformin was highest among vitamin B12 deficient group (1,981 ± 222 mg; P = 0.004).

Conclusion: The prevalence of vitamin B12 deficiency is considerable among diabetic patients on metformin therapy.

Further research is needed to confirm the need for routine screening and monitoring

American Psychological Association (APA)

al-Hamdi, Ahmad A.& Al-Gahhafi, Muhammad& al-Rushdi, Shihab& Jaju, Sanjay& al-Mamari, Ali& al-Mahrezi, Abd al-Aziz. 2020. Vitamin B12 deficiency in diabetic patients on metformin therapy : a cross-sectional study from Oman. Sultan Qaboos University Medical Journal،Vol. 20, no. 1, pp.90-94.
https://search.emarefa.net/detail/BIM-956845

Modern Language Association (MLA)

al-Hamdi, Ahmad A.…[et al.]. Vitamin B12 deficiency in diabetic patients on metformin therapy : a cross-sectional study from Oman. Sultan Qaboos University Medical Journal Vol. 20, no. 1 (Feb. 2020), pp.90-94.
https://search.emarefa.net/detail/BIM-956845

American Medical Association (AMA)

al-Hamdi, Ahmad A.& Al-Gahhafi, Muhammad& al-Rushdi, Shihab& Jaju, Sanjay& al-Mamari, Ali& al-Mahrezi, Abd al-Aziz. Vitamin B12 deficiency in diabetic patients on metformin therapy : a cross-sectional study from Oman. Sultan Qaboos University Medical Journal. 2020. Vol. 20, no. 1, pp.90-94.
https://search.emarefa.net/detail/BIM-956845

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 93-94

Record ID

BIM-956845