A novel method for spectrophotometric determination of isopropamide iodide in pharmaceutical formulations Application to content uniformity testing
Other Title(s)
طريقة طيفية مبتكرة لتقدير الأيزو بروب أمايد إيودايد في مستحضراته الدوائية و تطبيق الطريقة لفحص الاتساق
Joint Authors
Yusuf, Aminah Wisam
Ahmad, Nayif Rahman
Umar, Farha Khalaf
Source
Iraqi National Journal of Chemistry
Issue
Vol. 18, Issue 2 (30 Jun. 2018), pp.85-92, 8 p.
Publisher
University of Babylon College of Sciences
Publication Date
2018-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
A simple, accurate, economical, and rapid spectrophotometric method for the determination of isopropamide iodide in pharmaceutical preparation (tablets) has been developed.
The method is based on the reaction of isopropamide iodide and sodium nitrite in sulfuric acid medium to form iodine which shows maximum absorbance at 449 nm.
Beer,s law was obeyed in the concentration range ) 20-240µg/ml).
The molar absorptivity and Sandell,s sensitivity of the colored complex are 0.67×103 l/mol.cm.
and 0.717 ng/cm2 respectively .The limits of detection and quantization are 5.8 and 17.4 µg/ml respectively.
The analytical parameters were optimized and the method was successfully applied to the determination of isopropamide iodide in pure form and its tablets form.
American Psychological Association (APA)
Ahmad, Nayif Rahman& Umar, Farha Khalaf& Yusuf, Aminah Wisam. 2018. A novel method for spectrophotometric determination of isopropamide iodide in pharmaceutical formulations Application to content uniformity testing. Iraqi National Journal of Chemistry،Vol. 18, no. 2, pp.85-92.
https://search.emarefa.net/detail/BIM-957955
Modern Language Association (MLA)
Ahmad, Nayif Rahman…[et al.]. A novel method for spectrophotometric determination of isopropamide iodide in pharmaceutical formulations Application to content uniformity testing. Iraqi National Journal of Chemistry Vol. 18, no. 2 (2018), pp.85-92.
https://search.emarefa.net/detail/BIM-957955
American Medical Association (AMA)
Ahmad, Nayif Rahman& Umar, Farha Khalaf& Yusuf, Aminah Wisam. A novel method for spectrophotometric determination of isopropamide iodide in pharmaceutical formulations Application to content uniformity testing. Iraqi National Journal of Chemistry. 2018. Vol. 18, no. 2, pp.85-92.
https://search.emarefa.net/detail/BIM-957955
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 90-91
Record ID
BIM-957955