Management of neovascularization in recurrent herpetic keratitis

Abstract EN

Herpetic stromal keratitis activates a cascade of inflammatory processes that stimulate angiogenic factors such as VEGF (Vascular Endothelial Growth Factor) causing the development of blood vessels in the cornea.

In this case report, we describe an unusual case of a 35-year-old man with a known history of herpetic keratitis presenting to the emergency department with pain, haziness and itchiness of the right eye due to extensive neovascularization at the inferotemporal sclera of the corneal stroma extending to the 3 o’clock position.

Acyclovir, anti-VEGF (avastin) and argon laser were used in successfully managing the patient.

The triple therapy reversed neovascularization and prevented its further extension, leading to a good prognosis for the patient