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Synthesis and characterization of heterocyclic compounds derived from 1, 1-bis (4-aminophenyl) cyclohexane and their : study biological activity
Other Title(s)
تحضير و تشخيص المركبات غير المتجانسة المشتقة م 1، 1-ثنائي (٤-أميتوهببيل) سيكلوهكسان و : دراسة نشاطها البايولوجي
Joint Authors
Abd Allah, Ibtihal Qahtan
Nayif, Ulfat Abd
Gharib, Halah Muhammad
Jinzil, Nahidah Abd Allah
Source
Iraqi National Journal of Chemistry
Issue
Vol. 17, Issue 4 (31 Dec. 2017), pp.210-225, 16 p.
Publisher
University of Babylon College of Sciences
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
16
Main Subjects
Abstract EN
Synthesized and characterization of new sulfonamide derivatives ( schiff base , ,azo , azide, chalcone and 1,2,3- triazole) derived from (1, 1- bis (4- aminophenyl) cyclohexane [A1] ).
The synthesis compound [A2] include the reaction of compound [A1] with Toluene -4- Sulfonyl chloride while the azo compound [A3] produce from the reaction of diazonium salt with salicylaldehyde , then the azo compound [A3] were converted to chalcone derivative [A4] by reaction the azo compound [A3] with acetophenone .
Afterward reflux the azo compound with 2-amino pyrimidine to formation schiff base [A5] .
Azide derivative [A6] synthesized via the reaction of diazonium salt with sodium azide .
The new 1,2,3- triazole derivatives [A7,A8] were obtained from treatment azide compound[A6] with each ethyl acetoacetate and acetyl acetone ,respectively .
The structures of the compounds were confirmed by 1HNMR, 13CNMR, FT-IR spectroscopy and (C.H.N.) elementary analysis.
The synthesis compounds were evaluated1 for1antibacterial1(Staphylococcus1aureus , Becillus Cereus, Escherichia1coli, Pseudomonas1aeruginosa1and 1anti-fungal1 (Aspergillus1niger1 and Aspergillus1 fumigatus1by serial dilution1 method.
American Psychological Association (APA)
Nayif, Ulfat Abd& Abd Allah, Ibtihal Qahtan& Gharib, Halah Muhammad& Jinzil, Nahidah Abd Allah. 2017. Synthesis and characterization of heterocyclic compounds derived from 1, 1-bis (4-aminophenyl) cyclohexane and their : study biological activity. Iraqi National Journal of Chemistry،Vol. 17, no. 4, pp.210-225.
https://search.emarefa.net/detail/BIM-958084
Modern Language Association (MLA)
Nayif, Ulfat Abd…[et al.]. Synthesis and characterization of heterocyclic compounds derived from 1, 1-bis (4-aminophenyl) cyclohexane and their : study biological activity. Iraqi National Journal of Chemistry Vol. 17, no. 4 (2017), pp.210-225.
https://search.emarefa.net/detail/BIM-958084
American Medical Association (AMA)
Nayif, Ulfat Abd& Abd Allah, Ibtihal Qahtan& Gharib, Halah Muhammad& Jinzil, Nahidah Abd Allah. Synthesis and characterization of heterocyclic compounds derived from 1, 1-bis (4-aminophenyl) cyclohexane and their : study biological activity. Iraqi National Journal of Chemistry. 2017. Vol. 17, no. 4, pp.210-225.
https://search.emarefa.net/detail/BIM-958084
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 222-224
Record ID
BIM-958084