Preparation and evaluation of local polyvalent inactivated salmonella enterica serovar enteritidis, typhimurium and kentucky vaccine for protection against salmonellosis in chickens in Egypt
Other Title(s)
تحضير و تقييم لقاح متعدد العترات للحماية ضد ميكروبات السالمونيلا و كفاءته في يرامج التحصين في الدواجن
Joint Authors
Ibrahim, Rasha Abd al-Munim
Khafaji, Ahmad Ahmad Rifat
Salamah, Salim Salim
Source
Suez Canal Veterinary Medicine Journal
Issue
Vol. 23, Issue 1 (30 Jun. 2018), pp.95-111, 17 p.
Publisher
Suez Canal University Faculty of Veterinary Medicine
Publication Date
2018-06-30
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Salmonellosis is one of the most important bacterial diseases affecting poultry.
Its importance is derived from the loss in productivity in affected birds and the hazard it causes for public health.
Vaccination is one of the best means for controlling salmonellosis in birds.
In the present study the immunizing and protective efficacy of a newly locally prepared polyvalent inactivated oil adjuvanted Salmonella subspecies enterica serovar Typhimurium, Enteritidis and Kentucky vaccine had been studied.
Evaluation of the prepared vaccine were adopted based on the standard regulations and comparison with the commercially available vaccine.
This newly locally prepared vaccine was proved to be sterile and safe even if used in double field dose.
Also the residues of both merthiolates and formaldhyde were under the standard permissible limit.
Potency of the prepared vaccine was evaluated serologically using ELISA and by using challenge test.
Challenge test showed 70 % protection when adopted post single dose vaccination raised to 82 % post booster dose vaccination when Salmonella Typhimurium virulent strain was used meanwhile it were 72 % and 84 % when virulent Salmonella Enteritidis was used and were 74 % and 86 % when Salmonella Kentucky virulent strain was used.
From the obtained results, the locally prepared vaccine had the advantages over the commercial one allover the experimentation period and it be concluded that the locally prepared polyvalent Salmonella vaccine induced significant protection rates with higher antibody response in the vaccinated birds.
Also it could be recommended that the production of local vaccine for usage in Egyptian farms is much better than importation of commercial vaccine.
American Psychological Association (APA)
Khafaji, Ahmad Ahmad Rifat& Salamah, Salim Salim& Ibrahim, Rasha Abd al-Munim. 2018. Preparation and evaluation of local polyvalent inactivated salmonella enterica serovar enteritidis, typhimurium and kentucky vaccine for protection against salmonellosis in chickens in Egypt. Suez Canal Veterinary Medicine Journal،Vol. 23, no. 1, pp.95-111.
https://search.emarefa.net/detail/BIM-958220
Modern Language Association (MLA)
Khafaji, Ahmad Ahmad Rifat…[et al.]. Preparation and evaluation of local polyvalent inactivated salmonella enterica serovar enteritidis, typhimurium and kentucky vaccine for protection against salmonellosis in chickens in Egypt. Suez Canal Veterinary Medicine Journal Vol. 23, no. 1 (2018), pp.95-111.
https://search.emarefa.net/detail/BIM-958220
American Medical Association (AMA)
Khafaji, Ahmad Ahmad Rifat& Salamah, Salim Salim& Ibrahim, Rasha Abd al-Munim. Preparation and evaluation of local polyvalent inactivated salmonella enterica serovar enteritidis, typhimurium and kentucky vaccine for protection against salmonellosis in chickens in Egypt. Suez Canal Veterinary Medicine Journal. 2018. Vol. 23, no. 1, pp.95-111.
https://search.emarefa.net/detail/BIM-958220
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 108-111
Record ID
BIM-958220