Hepato-protective effect of vitamin c extract from kiwifruit on hepatic injury induced by monosodium glutamate
Joint Authors
Fudah, Ahmad M. A.
Ibrahim, al-Sayyid I. E.
al-Shirbini, E. S.
Gouida, Muna S.
Source
Suez Canal Veterinary Medicine Journal
Issue
Vol. 24, Issue 1 (30 Jun. 2019), pp.27-36, 10 p.
Publisher
Suez Canal University Faculty of Veterinary Medicine
Publication Date
2019-06-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Human and animal studies have shown that some drugs and chemical agents have potential hepatotoxic effects.
The hepatotoxic effect of drugs and some chemical agents like MSG as flavor enhancer is reported to be associated with the generation of reactive oxygen species (ROS) and lipid peroxidation in the liver.
This mechanism has led to continuous evaluation of the hepatoprotective effect of antioxidants like vitamin C in humans and animals.
This study included 36 adult male albino rats divided into six experimental groups.
Liver function tests, oxidative stress and anti-oxidant status were estimated.
Moreover, histopathological investigations of liver tissues before and after treatment.
There are significant changes in liver function tests, oxidative stress and antioxidant parameters noted after treatment with vitamin C.
Moreover, the photomicrograph of liver tissue section show significant improvement in-group treated with vitamin C after MSG administration.
Vitamin C is an essential co-factor involved in many biochemical functions and acts as an electron donor or reducing agent.
In this study it is observe that vitamin C has hepatoprotective effect through antioxidant and anti-lipid peroxidation mechanisms.
American Psychological Association (APA)
Fudah, Ahmad M. A.& Ibrahim, al-Sayyid I. E.& Gouida, Muna S.& al-Shirbini, E. S.. 2019. Hepato-protective effect of vitamin c extract from kiwifruit on hepatic injury induced by monosodium glutamate. Suez Canal Veterinary Medicine Journal،Vol. 24, no. 1, pp.27-36.
https://search.emarefa.net/detail/BIM-958658
Modern Language Association (MLA)
Fudah, Ahmad M. A.…[et al.]. Hepato-protective effect of vitamin c extract from kiwifruit on hepatic injury induced by monosodium glutamate. Suez Canal Veterinary Medicine Journal Vol. 24, no. 1 (2019), pp.27-36.
https://search.emarefa.net/detail/BIM-958658
American Medical Association (AMA)
Fudah, Ahmad M. A.& Ibrahim, al-Sayyid I. E.& Gouida, Muna S.& al-Shirbini, E. S.. Hepato-protective effect of vitamin c extract from kiwifruit on hepatic injury induced by monosodium glutamate. Suez Canal Veterinary Medicine Journal. 2019. Vol. 24, no. 1, pp.27-36.
https://search.emarefa.net/detail/BIM-958658
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 34-36
Record ID
BIM-958658