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The diagnostic value of leukocyte esterase reagent dip-stick in spontaneous bacterial peritonitis diagnosis in patients with liver cirrhosis
Joint Authors
Jad, Amal
al-Nimr, Nadir A.
Sad, Muhammad
Source
Suez Canal University Medical Journal
Issue
Vol. 22, Issue 1 (30 Jun. 2019), pp.56-63, 8 p.
Publisher
Suez Canal University Faculty of Medicine
Publication Date
2019-06-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background: Spontaneous bacterial peritonitis (SBP) is a serious complication of advanced liver cirrhosis which requires rapid diagnosis for the initiation of proper antibiotic therapy.
Manual examination of ascetic fluid is a rather time-consuming procedure.
The leukocyte esterase (LE) reagent dipstick is based on the esterase activity of activated granulocytes which reacts with an ester‑releasing hydroxyphenylpyrrole causing a color change in the azo dye of reagent strip.
Aim: the aim of this study was to evaluate the diagnostic value of leukocyte esterase reagent dipstick in SBP diagnosis in patients with liver cirrhosis attending Suez Canal University Hospital.
Methods: ascetic fluid cell count using the counting chamber method was compared to Leucocyte Esterase strip rapid test in two groups of patients (65 ABP vs 65 non-SBP).
The strips were read in 120 seconds using colorimetric 5-grade scale (from 0 to 4).
The grades (0-2) were considered a negative test while grades (3-4) were considered a positive one.
Results: Comparison of the SBP +ve and -ve groups showed a sensitivity of LE strips of (82%) with a high specificity (94 %), PPV (93 %) and NPV (84 %) for the diagnosis of SBP.
A good correlation between the LE strip color grade and the ascetic fluid PMNL cell count number (P<0.05) Conclusion: the leukocyte esterase reagent dipstick test is a rather specific, rapid, inexpensive and simple bedside method for diagnosis of SBP method for.
A negative LE test result excludes SBP with a high accuracy.
American Psychological Association (APA)
Jad, Amal& al-Nimr, Nadir A.& Sad, Muhammad. 2019. The diagnostic value of leukocyte esterase reagent dip-stick in spontaneous bacterial peritonitis diagnosis in patients with liver cirrhosis. Suez Canal University Medical Journal،Vol. 22, no. 1, pp.56-63.
https://search.emarefa.net/detail/BIM-958777
Modern Language Association (MLA)
Jad, Amal…[et al.]. The diagnostic value of leukocyte esterase reagent dip-stick in spontaneous bacterial peritonitis diagnosis in patients with liver cirrhosis. Suez Canal University Medical Journal Vol. 22, no. 1 (2019), pp.56-63.
https://search.emarefa.net/detail/BIM-958777
American Medical Association (AMA)
Jad, Amal& al-Nimr, Nadir A.& Sad, Muhammad. The diagnostic value of leukocyte esterase reagent dip-stick in spontaneous bacterial peritonitis diagnosis in patients with liver cirrhosis. Suez Canal University Medical Journal. 2019. Vol. 22, no. 1, pp.56-63.
https://search.emarefa.net/detail/BIM-958777
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 62-63
Record ID
BIM-958777