Renal toxicity of titanium dioxide nanoparticlesin male albino rats
Joint Authors
Muhammad, Hana Mahmud
Abduh, Kh. A.
al-Nahhas, al-Shayma
Khalifah, Ahlam G.
Musaylihi, Wala Abd al-Rahman
Source
Journal of Veterinary Medical Research
Issue
Vol. 24, Issue 2 (31 Mar. 2018)9 p.
Publisher
Beni-Suef University Faculty of Veterinary Medicine
Publication Date
2018-03-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Nanoparticles have many characteristics that make them suitable for biological and medical applications.
Uptake of thesenano particulates into animals and humans bodiesthrough different routes may exhibit potential side effects.
Titanium dioxide (TiO2) is a common additivethat is increasingly used in consumer products, food,pharmaceutical dosage forms and cosmetic articles.
In this study, the effects of oral administration of TiO2 nanoparticles (500 mg| kg .bw) for 60 days were investigated on kidney function and histopathological changes.
The body weight gain and kidney/body weight ratio showed no significant changes in comparison with control group.
There was a significant decrease in total thiol levels in kidney homogenate, the biochemical changes was supported by histopathologicalultration.
In conclusion the data shows that the oral administration of TiO2 NPs may lead to renal toxicity in experimental rats.
American Psychological Association (APA)
Abduh, Kh. A.& Musaylihi, Wala Abd al-Rahman& Muhammad, Hana Mahmud& al-Nahhas, al-Shayma& Khalifah, Ahlam G.. 2018. Renal toxicity of titanium dioxide nanoparticlesin male albino rats. Journal of Veterinary Medical Research،Vol. 24, no. 2.
https://search.emarefa.net/detail/BIM-962089
Modern Language Association (MLA)
Abduh, Kh. A.…[et al.]. Renal toxicity of titanium dioxide nanoparticlesin male albino rats. Journal of Veterinary Medical Research Vol. 24, no. 2 (2018).
https://search.emarefa.net/detail/BIM-962089
American Medical Association (AMA)
Abduh, Kh. A.& Musaylihi, Wala Abd al-Rahman& Muhammad, Hana Mahmud& al-Nahhas, al-Shayma& Khalifah, Ahlam G.. Renal toxicity of titanium dioxide nanoparticlesin male albino rats. Journal of Veterinary Medical Research. 2018. Vol. 24, no. 2.
https://search.emarefa.net/detail/BIM-962089
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-962089