Incidence of toxoplasmosis in psoriasis patients and possible correlation with tumor necrosis factor-α

Other Title(s)

الإصابة بداء المقوسات في مرضى الصدفية و علاقته مع عامل نخر الورم-α

Joint Authors

Musa, Isra Salim
Al Isa, Yasir Abd al-Husayn
Zughayr, Khawlah Hawari
Sahib, Intisar Jabbar

Source

Baghdad Science Journal

Issue

Vol. 17, Issue 1 (sup) (31 Mar. 2020), pp.214-219, 6 p.

Publisher

University of Baghdad College of Science for Women

Publication Date

2020-03-31

Country of Publication

Iraq

No. of Pages

6

Main Topic

Diseases

Topics

Abstract EN

Toxoplasma gondii is an opportunistic parasite in immune-compromised persons.

The prevalence of toxoplasmosis in psoriasis patients is investigated.

In addition, the treatment effect on psoriasis patients infected with toxoplasmosis through evaluating Tumor Necrosis Factor-α (TNF-α) cytokine levels is studied.

Blood samples were collected from 130 individuals who involved 60 control samples and 70 samples with psoriasis.

They attended Medical City Hospital in Baghdad province from October 2017 - February 2018.

Then, the anti- T.

gondii antibodies (IgM and IgG) and TNF- α in the sera were determined via the enzyme linked immune-sorbent assay.

The highest rate of anti-Toxoplasma IgG was in psoriasis patients before treatment, it was 45 (64.29%) compared with the control which was 33 (55.00%), while the highest sero-positive rate of T.

gondii IgM in the control group was 14 (23.33%) compared with patients with psoriasis 10 (14.29%).

The highest rate of toxoplasmosis was in the age group (21-30) years in psoriasis patients which was 14 (31.82%).

In addition, the TNF- α levels in psoriatic patients before treatment were 180.2±2.2 µg/ml, and after treatment were 223.3±41.1 µg/ml compared with the healthy control group 90.5±1.9 µg/ml.

These findings suggest that incidental rate of toxoplasmosis is higher in psoriasis patients.

Thus, the incidental rate of toxoplasmosis could be considered as an indication to the high risk of psoriasis.

American Psychological Association (APA)

Sahib, Intisar Jabbar& Al Isa, Yasir Abd al-Husayn& Musa, Isra Salim& Zughayr, Khawlah Hawari. 2020. Incidence of toxoplasmosis in psoriasis patients and possible correlation with tumor necrosis factor-α. Baghdad Science Journal،Vol. 17, no. 1 (sup), pp.214-219.
https://search.emarefa.net/detail/BIM-970024

Modern Language Association (MLA)

Sahib, Intisar Jabbar…[et al.]. Incidence of toxoplasmosis in psoriasis patients and possible correlation with tumor necrosis factor-α. Baghdad Science Journal Vol. 17, no. 1 (Supplement) (Mar. 2020), pp.214-219.
https://search.emarefa.net/detail/BIM-970024

American Medical Association (AMA)

Sahib, Intisar Jabbar& Al Isa, Yasir Abd al-Husayn& Musa, Isra Salim& Zughayr, Khawlah Hawari. Incidence of toxoplasmosis in psoriasis patients and possible correlation with tumor necrosis factor-α. Baghdad Science Journal. 2020. Vol. 17, no. 1 (sup), pp.214-219.
https://search.emarefa.net/detail/BIM-970024

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 217-208

Record ID

BIM-970024