Lack of association between LCS6 Variant in KRAS gene with the occurrence of breast tumors in Iraqi women
Other Title(s)
فقدان العلاقة بين التباين الوراثي LCS6 في جين KRAS مع حدوث الإصابة بأورام الثدي في النساء العراقيات
Joint Authors
Salih, Wiam Abd al-Fattah
al-Haddad, Ruya Hadi
Jasim, Hamid Majid
Source
Issue
Vol. 17, Issue 2 (30 Jun. 2020), pp.426-430, 5 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2020-06-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Abstract EN
Breast cancer is the most commonly diagnosed cancer and remains one of the main reasons of cancer-related mortality in women worldwide.
KRAS variant rs61764370 (T>G) is associated with an increased risk of occurrence of many cancers, Here The case-control study was accomplished on 135 women including 45 women with breast cancer patients, 45 women with benign breast lesions and 45 healthy women to analyze the association of KRAS variant rs (61764370 T>G) with breast cancer.
LCS 6 variant in KRAS gene was amplified by using specific primers, then genotype was detected after sequencing the PCR products.
The results showed that the genotype and allele frequency of TT and GT allele of KRAS gene were statistically non-significant (p< 0.01) among breast cancer patients and breast benign lesions compared with healthy controls in Iraqi women.
American Psychological Association (APA)
al-Haddad, Ruya Hadi& Jasim, Hamid Majid& Salih, Wiam Abd al-Fattah. 2020. Lack of association between LCS6 Variant in KRAS gene with the occurrence of breast tumors in Iraqi women. Baghdad Science Journal،Vol. 17, no. 2, pp.426-430.
https://search.emarefa.net/detail/BIM-970235
Modern Language Association (MLA)
al-Haddad, Ruya Hadi…[et al.]. Lack of association between LCS6 Variant in KRAS gene with the occurrence of breast tumors in Iraqi women. Baghdad Science Journal Vol. 17, no. 2 (2020), pp.426-430.
https://search.emarefa.net/detail/BIM-970235
American Medical Association (AMA)
al-Haddad, Ruya Hadi& Jasim, Hamid Majid& Salih, Wiam Abd al-Fattah. Lack of association between LCS6 Variant in KRAS gene with the occurrence of breast tumors in Iraqi women. Baghdad Science Journal. 2020. Vol. 17, no. 2, pp.426-430.
https://search.emarefa.net/detail/BIM-970235
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 429-430
Record ID
BIM-970235
