Correlation of serum concentration cyclin-dependent kinase 4 and cyclin-dependent kinase 6 with Breast Cancer in Babylon Province
Joint Authors
al-Uwaydi, Daliyah Shakir
al-Awwad, Ala Sadiq
al-Ghazzali, Muayyad E.
Source
Issue
Vol. 17, Issue 2 (30 Jun. 2020), pp.199-203, 5 p.
Publisher
University of Babylon College of Medicine
Publication Date
2020-06-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
Objectives : The goal of this study to estimate the correlation between breast cancer and cyclin-dependent kinase 4 (CDK4)\CDK6 enzyme concentrations in the occurrence of breast cancer and breast cancer subtypes.
Methods: A total of 80 breast cancer patients are subdivided according to molecular classification into four groups, Luminal A, Luminal B, Her2 / neu enriched, and TPN and 80 healthy individuals as control were enrolled ; biochemical tests and body mass index were assayed.
Results : No significant differences were found between patients and control groups and no significant differences were found among breast cancer subtypes in the concentrations of CDK4 (P > 0.05).
There were no significant differences found between patients and control groups and no significant difference in the CDK6 concentration among subtypes groups (P > 0.05).
The correlation between age, CDK4, and CDK6 in cases and control revealed that the correlation was absent between age, CDK4, and CDK6 concentration, except a weak positive correlation was found between CDK4 and CDK6 concentrations.
Conclusion : There was no significant difference in serum levels of CDK4 and serum level of CDK6 between case and control and among patient subtypes.
American Psychological Association (APA)
al-Uwaydi, Daliyah Shakir& al-Ghazzali, Muayyad E.& al-Awwad, Ala Sadiq. 2020. Correlation of serum concentration cyclin-dependent kinase 4 and cyclin-dependent kinase 6 with Breast Cancer in Babylon Province. Medical Journal of Babylon،Vol. 17, no. 2, pp.199-203.
https://search.emarefa.net/detail/BIM-972616
Modern Language Association (MLA)
al-Uwaydi, Daliyah Shakir…[et al.]. Correlation of serum concentration cyclin-dependent kinase 4 and cyclin-dependent kinase 6 with Breast Cancer in Babylon Province. Medical Journal of Babylon Vol. 17, no. 2 (Jun. 2020), pp.199-203.
https://search.emarefa.net/detail/BIM-972616
American Medical Association (AMA)
al-Uwaydi, Daliyah Shakir& al-Ghazzali, Muayyad E.& al-Awwad, Ala Sadiq. Correlation of serum concentration cyclin-dependent kinase 4 and cyclin-dependent kinase 6 with Breast Cancer in Babylon Province. Medical Journal of Babylon. 2020. Vol. 17, no. 2, pp.199-203.
https://search.emarefa.net/detail/BIM-972616
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 203
Record ID
BIM-972616