Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital
Joint Authors
Mallya, Sneha Deepak
Reddy T, Sravan Kumar
Kamath, Asha
Pandey, Akhilesh Kumar
Saravu, Kavitha
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Longer survival due to use of antiretroviral therapy (ART) has made human immunodeficiency virus- (HIV-) infected individuals prone to chronic diseases such as diabetes, hypertension, and cardiovascular diseases (CVD).
Metabolic syndrome (MS), a constellation of risk factors which increase chances of the cardiovascular disease and diabetes, can increase the morbidity and mortality among this population.
Hence, the present study was conducted with the objectives of estimating the prevalence and determinants of MS among ART naïve and ART-treated patients and assess their 5-year CVD risk using the reduced version of Data Collection on Adverse Effects of Anti-HIV Drugs (D : A : D) risk prediction model (D : A : D(R)).
This hospital-based cross-sectional study included 182 adults aged ≥ 18 years.
MS was defined using the National Cholesterol Education Program-Adult Treatment Panel-3 (NCEP ATP-3) criteria.
Univariate and multivariate logistic regressions were done to identify the factors associated with MS.
Prevalence of MS was 40.1% (95% confidence interval (CI) = 33.0%–47.2%).
About 24.7% of the participants had at least a single criterion for MS.
Age >45 years (adjusted odds ratio (AOR) = 2.3; 95% CI = 1.1–4.9, p<0.018) and body mass index (BMI) > 23 kg/m2 (AOR = 6.4; 95% CI = 3.1–13.1, p<0.001) were positively associated with MS, whereas daily consumption of high sugar items was inversely associated (AOR = 0.2; 95% CI = 0.1–0.5, p<0.001).
More than 50% of the participants were found to have moderate or high 5-year CVD risk.
Observed prevalence of MS among HIV patients was higher than other studies done in India.
Considering a sizeable number of participants to be having moderate to high CVD risk, culturally appropriate lifestyle interventions need to be planned.
American Psychological Association (APA)
Mallya, Sneha Deepak& Reddy T, Sravan Kumar& Kamath, Asha& Pandey, Akhilesh Kumar& Saravu, Kavitha. 2020. Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital. AIDS Research and Treatment،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-986226
Modern Language Association (MLA)
Mallya, Sneha Deepak…[et al.]. Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital. AIDS Research and Treatment No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-986226
American Medical Association (AMA)
Mallya, Sneha Deepak& Reddy T, Sravan Kumar& Kamath, Asha& Pandey, Akhilesh Kumar& Saravu, Kavitha. Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital. AIDS Research and Treatment. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-986226
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-986226