Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital

Joint Authors

Mallya, Sneha Deepak
Reddy T, Sravan Kumar
Kamath, Asha
Pandey, Akhilesh Kumar
Saravu, Kavitha

Source

AIDS Research and Treatment

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-10-28

Country of Publication

Egypt

No. of Pages

8

Main Topic

Diseases
Medicine

Abstract EN

Longer survival due to use of antiretroviral therapy (ART) has made human immunodeficiency virus- (HIV-) infected individuals prone to chronic diseases such as diabetes, hypertension, and cardiovascular diseases (CVD).

Metabolic syndrome (MS), a constellation of risk factors which increase chances of the cardiovascular disease and diabetes, can increase the morbidity and mortality among this population.

Hence, the present study was conducted with the objectives of estimating the prevalence and determinants of MS among ART naïve and ART-treated patients and assess their 5-year CVD risk using the reduced version of Data Collection on Adverse Effects of Anti-HIV Drugs (D : A : D) risk prediction model (D : A : D(R)).

This hospital-based cross-sectional study included 182 adults aged ≥ 18 years.

MS was defined using the National Cholesterol Education Program-Adult Treatment Panel-3 (NCEP ATP-3) criteria.

Univariate and multivariate logistic regressions were done to identify the factors associated with MS.

Prevalence of MS was 40.1% (95% confidence interval (CI) = 33.0%–47.2%).

About 24.7% of the participants had at least a single criterion for MS.

Age >45 years (adjusted odds ratio (AOR) = 2.3; 95% CI = 1.1–4.9, p<0.018) and body mass index (BMI) > 23 kg/m2 (AOR = 6.4; 95% CI = 3.1–13.1, p<0.001) were positively associated with MS, whereas daily consumption of high sugar items was inversely associated (AOR = 0.2; 95% CI = 0.1–0.5, p<0.001).

More than 50% of the participants were found to have moderate or high 5-year CVD risk.

Observed prevalence of MS among HIV patients was higher than other studies done in India.

Considering a sizeable number of participants to be having moderate to high CVD risk, culturally appropriate lifestyle interventions need to be planned.

American Psychological Association (APA)

Mallya, Sneha Deepak& Reddy T, Sravan Kumar& Kamath, Asha& Pandey, Akhilesh Kumar& Saravu, Kavitha. 2020. Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital. AIDS Research and Treatment،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-986226

Modern Language Association (MLA)

Mallya, Sneha Deepak…[et al.]. Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital. AIDS Research and Treatment No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-986226

American Medical Association (AMA)

Mallya, Sneha Deepak& Reddy T, Sravan Kumar& Kamath, Asha& Pandey, Akhilesh Kumar& Saravu, Kavitha. Determinants of Metabolic Syndrome and 5-Year Cardiovascular Risk Estimates among HIV-Positive Individuals from an Indian Tertiary Care Hospital. AIDS Research and Treatment. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-986226

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-986226