Viral Suppression and Its Associated Factors in HIV Patients on Highly Active Antiretroviral Therapy (HAART)‎: A Retrospective Study in the Ho Municipality, Ghana

Joint Authors

Lokpo, Sylvester Yao
Ofori-Attah, Patrick Jnr
Ameke, Louis Selassie
Obirikorang, Christian
Orish, Verner Ndudiri
Kpene, Godsway Edem
Agboli, Eric
Kye-Duodu, Gideon
Deku, John Gameli
Awadzi, Benedict Kwame
Noagbe, Mark
Tetteh Quarshie, Seyram

Source

AIDS Research and Treatment

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-02-13

Country of Publication

Egypt

No. of Pages

7

Main Topic

Diseases
Medicine

Abstract EN

The WHO targets to end HIV/AIDS as a public health problem by 2030.

The introduction of the ambitious “90-90-90” strategy to attain this target is expected to be achieved by the year 2020.

However, there is lack of regional data, especially on the third “90.” This study sought to assess the rate and associated factors of viral suppression among people living with HIV (PLWH) on highly active antiretroviral therapy (HAART) at the Antiretroviral Therapy (ART) Clinic in a Ghanaian health facility.

Method.

The study design was a retrospective analysis of secondary data of 284 HIV registrants on HAART for at least 6 months at the ART Clinic from July 2016 to April 2019.

Data on sociodemography including age, gender, marital status, education, and occupation as well as pharmacological (type of medication and duration on medication) and laboratory variable (current viral load results) were extracted from patients’ folders.

Viral suppression and failure were determined using the WHO definitions (viral suppression as viral load <1000 copies/ml and virologic failure ≥1000 copies/ml).

Regular clinic attendance (used as a proxy measure for medication adherence) was defined as consistent monthly clinic attendance for HAART medication and other clinical management within the past 12 months.

Results.

Out of the 284 HIV patients, 195 (69%) achieved viral suppression.

Of the 195 who were virally suppressed, 77 (39.5%) had undetectable levels, with a similar proportion (39.5%) achieving viral load results ranging from 20 to 200 copies/ml.

Moreover, 27 (13.8%) patients had viral load ranging from 201 to 500 copies/ml while 14 (7.2%) recorded viral load from 501 to 1000 copies/ml.

No clear pattern in the viral suppression rate was associated with the age groups (p=0.1152).

However, regular clinic attendance (used as proxy for medication adherence) (p<0.0001) and being on HAART for more than three (3) years (p=0.03) were associated with viral suppression.

Conclusion.

The rate of viral suppression among PLWH on HAART in the Ho municipality fell short of the WHO target.

However, the study identified regular ART clinic attendance and treatment >3 years as factors associated with viral suppression.

American Psychological Association (APA)

Lokpo, Sylvester Yao& Ofori-Attah, Patrick Jnr& Ameke, Louis Selassie& Obirikorang, Christian& Orish, Verner Ndudiri& Kpene, Godsway Edem…[et al.]. 2020. Viral Suppression and Its Associated Factors in HIV Patients on Highly Active Antiretroviral Therapy (HAART): A Retrospective Study in the Ho Municipality, Ghana. AIDS Research and Treatment،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-986242

Modern Language Association (MLA)

Lokpo, Sylvester Yao…[et al.]. Viral Suppression and Its Associated Factors in HIV Patients on Highly Active Antiretroviral Therapy (HAART): A Retrospective Study in the Ho Municipality, Ghana. AIDS Research and Treatment No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-986242

American Medical Association (AMA)

Lokpo, Sylvester Yao& Ofori-Attah, Patrick Jnr& Ameke, Louis Selassie& Obirikorang, Christian& Orish, Verner Ndudiri& Kpene, Godsway Edem…[et al.]. Viral Suppression and Its Associated Factors in HIV Patients on Highly Active Antiretroviral Therapy (HAART): A Retrospective Study in the Ho Municipality, Ghana. AIDS Research and Treatment. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-986242

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-986242