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Toxoplasma Rhoptries: Unique Secretory Organelles and Source of Promising Vaccine Proteins for Immunoprevention of Toxoplasmosis
Author
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-06-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Toxoplasma gondii is an obligate intracellular protozoan parasite classified in the phylum Apicomplexa, which includes numerous notable human and animal pathogens (Plasmodium species, Cryptosporidium species, Neospora caninum, etc.).
The invasive stages of apicomplexans are characterized by the presence of an apical complex composed of specialized cytoskeletal and secretory organelles, including rhoptries.
Rhoptries, unique apical secretory organelles shared exclusively by all apicomplexan parasites, are known to be involved in an active parasite's penetration into the host cell associated with the biogenesis of specific intracellular compartment, parasitophorous vacuole in which the parasite multiplies intensively, avoiding intracellular killing.
Due to the key biological role of rhoptries, rhoptry proteins have recently become vaccine candidates for the prevention of several parasitoses, toxoplasmosis among them.
The article presents current data on T.
gondii rhoptries biology and new approaches to the development of effective vaccines against toxoplasmosis using rhoptry antigens.
American Psychological Association (APA)
Dlugonska, Henryka. 2008. Toxoplasma Rhoptries: Unique Secretory Organelles and Source of Promising Vaccine Proteins for Immunoprevention of Toxoplasmosis. BioMed Research International،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-987792
Modern Language Association (MLA)
Dlugonska, Henryka. Toxoplasma Rhoptries: Unique Secretory Organelles and Source of Promising Vaccine Proteins for Immunoprevention of Toxoplasmosis. BioMed Research International No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-987792
American Medical Association (AMA)
Dlugonska, Henryka. Toxoplasma Rhoptries: Unique Secretory Organelles and Source of Promising Vaccine Proteins for Immunoprevention of Toxoplasmosis. BioMed Research International. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-987792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-987792