Role of C-Peptide in the Regulation of Microvascular Blood Flow
Joint Authors
Weber, Matthias M.
Pfützner, Andreas
Wilhelm, B.
Forst, Thomas
Kunt, Thomas
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-07-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
During the recent years, the role of C-peptide, released from the pancreatic beta cell, in regulating microvascular blood flow, has received increasing attention.
In type 1 diabetic patients, intravenous application of C-peptide in physiological concentrations was shown to increase microvascular blood flow, and to improve microvascular endothelial function and the endothelial release of NO.
C-peptide was shown to impact microvascular blood flow by several interactive pathways, like stimulating Na+K+ATPase or the endothelial release of NO.
There is increasing evidence, that in patients with declining beta cell function, the lack of C-peptide secretion might play a putative role in the development of microvascular blood flow abnormalities, which go beyond the effects of declining insulin secretion or increased blood glucose levels.
American Psychological Association (APA)
Forst, Thomas& Kunt, Thomas& Wilhelm, B.& Weber, Matthias M.& Pfützner, Andreas. 2008. Role of C-Peptide in the Regulation of Microvascular Blood Flow. Journal of Diabetes Research،Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-987997
Modern Language Association (MLA)
Forst, Thomas…[et al.]. Role of C-Peptide in the Regulation of Microvascular Blood Flow. Journal of Diabetes Research No. 2008 (2008), pp.1-8.
https://search.emarefa.net/detail/BIM-987997
American Medical Association (AMA)
Forst, Thomas& Kunt, Thomas& Wilhelm, B.& Weber, Matthias M.& Pfützner, Andreas. Role of C-Peptide in the Regulation of Microvascular Blood Flow. Journal of Diabetes Research. 2008. Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-987997
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-987997