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The Assessment of Autoimmunological Status and Prevalence of Different Forms of Celiac Disease among Children with Type 1 Diabetes Mellitus and Celiac Disease
Joint Authors
Deja, Grazyna
Jarosz-Chobot, Przemyslawa
Myrda, Anna
Siekiera, Urszula
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-01-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study aims to assess the autoimmunological status and forms of celiac disease (CD) among children with type 1 diabetes mellitus (T1DM) .
The study group comprises 27 patients at the mean age of 12.30 years (±SD 3.12).
The measurement of the level of diabetes-specific antibodies and organ-specific antibodies was gained at the T1DM-onset and repeated annually.
The following risk factors influencing time of CD diagnosis were analyzed: age, sex, T1DM duration, autoantibodies, and HLA-haplotype.
The prevalence of antibodies was GADA-74%, IAA-63%, IA2A-67%, ATA-11%, and ATG-4%.
The intestinal biopsy revealed in 19% no changes and in 77% stage 3 (Marsh scale).
In most cases, no clinical manifestation of CD was observed.
The diagnosis of Hashimoto's disease was made twice.
The negative correlation between the age at T1DM-onset and the interval between onset of T1DM and CD (r=‐0.35, p<.05) was noted.
The high-comorbidity ratio of CD and thyroiditis with T1DM demands regular screening tests especially in the first years after T1DM-onset.
American Psychological Association (APA)
Deja, Grazyna& Myrda, Anna& Jarosz-Chobot, Przemyslawa& Siekiera, Urszula. 2008. The Assessment of Autoimmunological Status and Prevalence of Different Forms of Celiac Disease among Children with Type 1 Diabetes Mellitus and Celiac Disease. Mediators of Inflammation،Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988144
Modern Language Association (MLA)
Deja, Grazyna…[et al.]. The Assessment of Autoimmunological Status and Prevalence of Different Forms of Celiac Disease among Children with Type 1 Diabetes Mellitus and Celiac Disease. Mediators of Inflammation No. 2008 (2008), pp.1-6.
https://search.emarefa.net/detail/BIM-988144
American Medical Association (AMA)
Deja, Grazyna& Myrda, Anna& Jarosz-Chobot, Przemyslawa& Siekiera, Urszula. The Assessment of Autoimmunological Status and Prevalence of Different Forms of Celiac Disease among Children with Type 1 Diabetes Mellitus and Celiac Disease. Mediators of Inflammation. 2008. Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988144
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988144