Therapeutic Potential of PPARγ Activation in Stroke
Author
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-04-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Stroke (focal cerebral ischemia) is a leading cause of death and disability among adult population.
Many pathological events including inflammation and oxidative stress during the acute period contributes to the secondary neuronal death leading the neurological dysfunction after stroke.
Transcriptional regulation of genes that promote these pathophysiological mechanisms can be an effective strategy to minimize the poststroke neuronal death.
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors known to be upstream to many inflammatory and antioxidant genes.
The goal of this review is to discuss the therapeutic potential and putative mechanisms of neuroprotection following PPAR activation after stroke.
American Psychological Association (APA)
Vemuganti, Raghu. 2008. Therapeutic Potential of PPARγ Activation in Stroke. PPAR Research،Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-988208
Modern Language Association (MLA)
Vemuganti, Raghu. Therapeutic Potential of PPARγ Activation in Stroke. PPAR Research No. 2008 (2008), pp.1-9.
https://search.emarefa.net/detail/BIM-988208
American Medical Association (AMA)
Vemuganti, Raghu. Therapeutic Potential of PPARγ Activation in Stroke. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-988208
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988208