PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis
Joint Authors
Racke, Michael K.
Lovett-Racke, Amy
Drew, Paul D.
Yang, Yuhong
Gocke, Anne R.
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-06-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
PPARs are members of the steroid hormone nuclear receptor superfamily and play an important role in the regulation of lipid metabolism, energy balance, artherosclerosis and glucose control.
Recent studies suggest that they play an important role in regulating inflammation.
This review will focus on PPAR-α regulation of the immune response.
We describe how PPAR-α regulates differentiation of T cells by transactivation and/or interaction with other transcription factors.
Moreover, PPAR-α agonists have been shown to ameliorate experimental autoimmune encephalomyelitis (EAE) in mice, suggesting that they could provide a therapy for human autoimmune diseases such as multiple sclerosis.
American Psychological Association (APA)
Yang, Yuhong& Gocke, Anne R.& Lovett-Racke, Amy& Drew, Paul D.& Racke, Michael K.. 2008. PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis. PPAR Research،Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988217
Modern Language Association (MLA)
Yang, Yuhong…[et al.]. PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis. PPAR Research No. 2008 (2008), pp.1-6.
https://search.emarefa.net/detail/BIM-988217
American Medical Association (AMA)
Yang, Yuhong& Gocke, Anne R.& Lovett-Racke, Amy& Drew, Paul D.& Racke, Michael K.. PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988217
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988217
