PPAR-γ: Therapeutic Potential for Multiple Sclerosis
Joint Authors
Racke, Michael K.
Drew, Paul D.
Xu, Jihong
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-06-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The role of peroxisome proliferator-activated receptors (PPARs) in altering lipid and glucose metabolism is well established.
More recent studies indicate that PPARs also play critical roles in controlling immune responses.
We and others have previously demonstrated that PPAR-γ agonists modulate the development of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS).
This review will discuss the cellular and molecular mechanisms by which these agonists are believed to modulate disease.
The therapeutic potential of PPAR-γ agonists in the treatment of multiple sclerosis will also be considered.
American Psychological Association (APA)
Drew, Paul D.& Xu, Jihong& Racke, Michael K.. 2008. PPAR-γ: Therapeutic Potential for Multiple Sclerosis. PPAR Research،Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-988226
Modern Language Association (MLA)
Drew, Paul D.…[et al.]. PPAR-γ: Therapeutic Potential for Multiple Sclerosis. PPAR Research No. 2008 (2008), pp.1-9.
https://search.emarefa.net/detail/BIM-988226
American Medical Association (AMA)
Drew, Paul D.& Xu, Jihong& Racke, Michael K.. PPAR-γ: Therapeutic Potential for Multiple Sclerosis. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-988226
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988226