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EBV-Associated Smooth Muscle Neoplasms: Solid Tumors Arising in the Presence of Immunosuppression and Autoimmune Diseases
Joint Authors
Maki, Robert G.
Moore Dalal, Kimberly
Antonescu, Cristina R.
DeMatteo, Ronald P.
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-11-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Epstein-Barr virus (EBV)-related smooth muscle neoplasms (SMNs) have been associated with immune dysregulation, most notably in patients who have undergone solid organ transplantation or in patients with HIV/AIDS.
Objective.
to report our experience with EBV-related neoplasms as well as describing the first EBV-related SMN in the setting of administration of glucocorticoids and the tumor necrosis factor inhibitor etanercept.
Design.
We have case reports, of minimum 3-year follow-up, 2002–2005.
Setting.
It was held in an academic and tertiary referral cancer center.
Patients.
Patients are with dysregulated immunity after solid organ transplantation, HIV/AIDS, or with psoriasis after treatment with etanercept.
Interventions.
There were discontinuation of etanercept, right hepatic trisegmentectomy, and chemotherapy.
Measurements.
We use survival as a measurement here.
Results.
Patients who were able to withstand reduction in immunosuppression survived.
Surgical resection or chemotherapy was successful in delaying progression of disease.
Limitations.
There was a relatively short follow-up for these slow-growing neoplasms.
Conclusion.
EBV-related SMNs have variable aggressiveness.
While chemotherapy may slow disease progression, resection and improving the host immune status provide the best opportunity for primary tumor control.
American Psychological Association (APA)
Moore Dalal, Kimberly& Antonescu, Cristina R.& DeMatteo, Ronald P.& Maki, Robert G.. 2008. EBV-Associated Smooth Muscle Neoplasms: Solid Tumors Arising in the Presence of Immunosuppression and Autoimmune Diseases. Complexity،Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988272
Modern Language Association (MLA)
Moore Dalal, Kimberly…[et al.]. EBV-Associated Smooth Muscle Neoplasms: Solid Tumors Arising in the Presence of Immunosuppression and Autoimmune Diseases. Complexity No. 2008 (2008), pp.1-6.
https://search.emarefa.net/detail/BIM-988272
American Medical Association (AMA)
Moore Dalal, Kimberly& Antonescu, Cristina R.& DeMatteo, Ronald P.& Maki, Robert G.. EBV-Associated Smooth Muscle Neoplasms: Solid Tumors Arising in the Presence of Immunosuppression and Autoimmune Diseases. Complexity. 2008. Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-988272
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988272