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Gene-Based Multiclass Cancer Diagnosis with Class-Selective Rejections
Joint Authors
Beauseroy, Pierre
Grall-Maës, Edith
Jrad, Nisrine
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-06-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Supervised learning of microarray data is receiving much attention in recent years.
Multiclass cancer diagnosis, based on selected gene profiles, are used as adjunct of clinical diagnosis.
However, supervised diagnosis may hinder patient care, add expense or confound a result.
To avoid this misleading, a multiclass cancer diagnosis with class-selective rejection is proposed.
It rejects some patients from one, some, or all classes in order to ensure a higher reliability while reducing time and expense costs.
Moreover, this classifier takes into account asymmetric penalties dependant on each class and on each wrong or partially correct decision.
It is based on ν-1-SVM coupled with its regularization path and minimizes a general loss function defined in the class-selective rejection scheme.
The state of art multiclass algorithms can be considered as a particular case of the proposed algorithm where the number of decisions is given by the classes and the loss function is defined by the Bayesian risk.
Two experiments are carried out in the Bayesian and the class selective rejection frameworks.
Five genes selected datasets are used to assess the performance of the proposed method.
Results are discussed and accuracies are compared with those computed by the Naive Bayes, Nearest Neighbor, Linear Perceptron, Multilayer Perceptron, and Support Vector Machines classifiers.
American Psychological Association (APA)
Jrad, Nisrine& Grall-Maës, Edith& Beauseroy, Pierre. 2009. Gene-Based Multiclass Cancer Diagnosis with Class-Selective Rejections. BioMed Research International،Vol. 2009, no. 2009, pp.1-10.
https://search.emarefa.net/detail/BIM-988403
Modern Language Association (MLA)
Jrad, Nisrine…[et al.]. Gene-Based Multiclass Cancer Diagnosis with Class-Selective Rejections. BioMed Research International No. 2009 (2009), pp.1-10.
https://search.emarefa.net/detail/BIM-988403
American Medical Association (AMA)
Jrad, Nisrine& Grall-Maës, Edith& Beauseroy, Pierre. Gene-Based Multiclass Cancer Diagnosis with Class-Selective Rejections. BioMed Research International. 2009. Vol. 2009, no. 2009, pp.1-10.
https://search.emarefa.net/detail/BIM-988403
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988403