Separation and Purification of Two Flavone Glucuronides from Erigeron multiradiatus (Lindl.)‎ Benth with Macroporous Resins

Joint Authors

Zhang, Hao
Luo, Pei
Zhang, Zhi-feng
Liu, Yuan

Source

BioMed Research International

Issue

Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2009-09-28

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Medicine

Abstract EN

Scutellarein-7-O-β-D-glucuronide (SG) and apigenin-7-O-β-D-glucuronide (AG) are two major bioactive constituents in Erigeron multiradiatus.

In this study, a simple method for preparative separation of the two flavone glucuronides was established with macroporous resins.

The performance and adsorption characteristics of eight macroporous resins including AB-8, HPD100, HPD450, HPD600, D100, D101, D141 and D160 had been evaluated.

The results confirmed that D141 resin was preferred choice, which offered the best adsorption and desorption capacities for the two glucuronides among the tested resins.

Sorption isotherms were constructed for D141 resin and fitted well to the Freundlich and Langmuir models (R2>0.95).

After one run treatment with D141 resin, the two constituents' content was increased from 2.14% and 1.34% in the crude extract of E.

multiradiatus to 24.63% and 18.42% in the final products with the recoveries of 82.5% and 85.4%, respectively.

The enrichment of SG and AG can be easily and effectively achieved via adsorption and desorption on D141 resin, and the method can be referenced for large-scale separation and purification of flavone glucuronides from herbal raw materials.

American Psychological Association (APA)

Zhang, Zhi-feng& Liu, Yuan& Luo, Pei& Zhang, Hao. 2009. Separation and Purification of Two Flavone Glucuronides from Erigeron multiradiatus (Lindl.) Benth with Macroporous Resins. BioMed Research International،Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-988465

Modern Language Association (MLA)

Zhang, Zhi-feng…[et al.]. Separation and Purification of Two Flavone Glucuronides from Erigeron multiradiatus (Lindl.) Benth with Macroporous Resins. BioMed Research International No. 2009 (2009), pp.1-8.
https://search.emarefa.net/detail/BIM-988465

American Medical Association (AMA)

Zhang, Zhi-feng& Liu, Yuan& Luo, Pei& Zhang, Hao. Separation and Purification of Two Flavone Glucuronides from Erigeron multiradiatus (Lindl.) Benth with Macroporous Resins. BioMed Research International. 2009. Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-988465

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-988465