A First-Stage Approximation to Identify New Imprinted Genes through Sequence Analysis of Its Coding Regions
Joint Authors
Daura-Oller, Elias
Paternáin, José L.
Cabré, Maria
Romeu, Antoni
Montero, Miguel A.
Source
International Journal of Genomics
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-03-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
In the present study, a positive training set of 30 known human imprinted gene coding regions are compared with a set of 72 randomly sampled human nonimprinted gene coding regions (negative training set) to identify genomic features common to human imprinted genes.
The most important feature of the present work is its ability to use multivariate analysis to look at variation, at coding region DNA level, among imprinted and non-imprinted genes.
There is a force affecting genomic parameters that appears through the use of the appropriate multivariate methods (principle components analysis (PCA) and quadratic discriminant analysis (QDA) to analyse quantitative genomic data.
We show that variables, such as CG content, [bp]% CpG islands, [bp]% Large Tandem Repeats, and [bp]% Simple Repeats, are able to distinguish coding regions of human imprinted genes.
American Psychological Association (APA)
Daura-Oller, Elias& Cabré, Maria& Montero, Miguel A.& Paternáin, José L.& Romeu, Antoni. 2009. A First-Stage Approximation to Identify New Imprinted Genes through Sequence Analysis of Its Coding Regions. International Journal of Genomics،Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-988527
Modern Language Association (MLA)
Daura-Oller, Elias…[et al.]. A First-Stage Approximation to Identify New Imprinted Genes through Sequence Analysis of Its Coding Regions. International Journal of Genomics No. 2009 (2009), pp.1-7.
https://search.emarefa.net/detail/BIM-988527
American Medical Association (AMA)
Daura-Oller, Elias& Cabré, Maria& Montero, Miguel A.& Paternáin, José L.& Romeu, Antoni. A First-Stage Approximation to Identify New Imprinted Genes through Sequence Analysis of Its Coding Regions. International Journal of Genomics. 2009. Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-988527
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988527