Emerging Vaccine Informatics
Joint Authors
Rappuoli, Rino
Chen, Robert T.
He, Yongqun Oliver
De Groot, Anne S.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-26, 26 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-15
Country of Publication
Egypt
No. of Pages
26
Main Subjects
Abstract EN
Vaccine informatics is an emerging research area that focuses on development and applications of bioinformatics methods that can be used to facilitate every aspect of the preclinical, clinical, and postlicensure vaccine enterprises.
Many immunoinformatics algorithms and resources have been developed to predict T- and B-cell immune epitopes for epitope vaccine development and protective immunity analysis.
Vaccine protein candidates are predictable in silico from genome sequences using reverse vaccinology.
Systematic transcriptomics and proteomics gene expression analyses facilitate rational vaccine design and identification of gene responses that are correlates of protection in vivo.
Mathematical simulations have been used to model host-pathogen interactions and improve vaccine production and vaccination protocols.
Computational methods have also been used for development of immunization registries or immunization information systems, assessment of vaccine safety and efficacy, and immunization modeling.
Computational literature mining and databases effectively process, mine, and store large amounts of vaccine literature and data.
Vaccine Ontology (VO) has been initiated to integrate various vaccine data and support automated reasoning.
American Psychological Association (APA)
He, Yongqun Oliver& Rappuoli, Rino& De Groot, Anne S.& Chen, Robert T.. 2011. Emerging Vaccine Informatics. BioMed Research International،Vol. 2010, no. 2010, pp.1-26.
https://search.emarefa.net/detail/BIM-988810
Modern Language Association (MLA)
He, Yongqun Oliver…[et al.]. Emerging Vaccine Informatics. BioMed Research International No. 2010 (Dec. 2010), pp.1-26.
https://search.emarefa.net/detail/BIM-988810
American Medical Association (AMA)
He, Yongqun Oliver& Rappuoli, Rino& De Groot, Anne S.& Chen, Robert T.. Emerging Vaccine Informatics. BioMed Research International. 2011. Vol. 2010, no. 2010, pp.1-26.
https://search.emarefa.net/detail/BIM-988810
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988810