Tight Junctions in Salivary Epithelium
Author
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-10
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Epithelial cell tight junctions (TJs) consist of a narrow belt-like structure in the apical region of the lateral plasma membrane that circumferentially binds each cell to its neighbor.
TJs are found in tissues that are involved in polarized secretions, absorption functions, and maintaining barriers between blood and interstitial fluids.
The morphology, permeability, and ion selectivity of TJ vary among different types of tissues and species.
TJs are very dynamic structures that assemble, grow, reorganize, and disassemble during physiological or pathological events.
Several studies have indicated the active role of TJ in intestinal, renal, and airway epithelial function; however, the functional significance of TJ in salivary gland epithelium is poorly understood.
Interactions between different combinations of the TJ family (each with their own unique regulatory proteins) define tissue specificity and functions during physiopathological processes; however, these interaction patterns have not been studied in salivary glands.
The purpose of this review is to analyze some of the current data regarding the regulatory components of the TJ that could potentially affect cellular functions of the salivary epithelium.
American Psychological Association (APA)
Baker, Olga J.. 2010. Tight Junctions in Salivary Epithelium. BioMed Research International،Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-988837
Modern Language Association (MLA)
Baker, Olga J.. Tight Junctions in Salivary Epithelium. BioMed Research International No. 2010 (Dec. 2010), pp.1-13.
https://search.emarefa.net/detail/BIM-988837
American Medical Association (AMA)
Baker, Olga J.. Tight Junctions in Salivary Epithelium. BioMed Research International. 2010. Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-988837
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988837