A New Method for the Evaluation of Vaccine Safety Based on Comprehensive Gene Expression Analysis
Joint Authors
Yamaguchi, Kazunari
Mizukami, Takuo
Ochiai, Masaki
Momose, Haruka
Hamaguchi, Isao
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
For the past 50 years, quality control and safety tests have been used to evaluate vaccine safety.
However, conventional animal safety tests need to be improved in several aspects.
For example, the number of test animals used needs to be reduced and the test period shortened.
It is, therefore, necessary to develop a new vaccine evaluation system.
In this review, we show that gene expression patterns are well correlated to biological responses in vaccinated rats.
Our findings and methods using experimental biology and genome science provide an important means of assessment for vaccine toxicity.
American Psychological Association (APA)
Momose, Haruka& Mizukami, Takuo& Ochiai, Masaki& Hamaguchi, Isao& Yamaguchi, Kazunari. 2010. A New Method for the Evaluation of Vaccine Safety Based on Comprehensive Gene Expression Analysis. BioMed Research International،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-988876
Modern Language Association (MLA)
Momose, Haruka…[et al.]. A New Method for the Evaluation of Vaccine Safety Based on Comprehensive Gene Expression Analysis. BioMed Research International No. 2010 (Dec. 2010), pp.1-7.
https://search.emarefa.net/detail/BIM-988876
American Medical Association (AMA)
Momose, Haruka& Mizukami, Takuo& Ochiai, Masaki& Hamaguchi, Isao& Yamaguchi, Kazunari. A New Method for the Evaluation of Vaccine Safety Based on Comprehensive Gene Expression Analysis. BioMed Research International. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-988876
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988876