Toward Engineering Synthetic Microbial Metabolism
Joint Authors
McArthur, George H.
Fong, Stephen S.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-11-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The generation of well-characterized parts and the formulation of biological design principles in synthetic biology are laying the foundation for more complex and advanced microbial metabolic engineering.
Improvements in de novo DNA synthesis and codon-optimization alone are already contributing to the manufacturing of pathway enzymes with improved or novel function.
Further development of analytical and computer-aided design tools should accelerate the forward engineering of precisely regulated synthetic pathways by providing a standard framework for the predictable design of biological systems from well-characterized parts.
In this review we discuss the current state of synthetic biology within a four-stage framework (design, modeling, synthesis, analysis) and highlight areas requiring further advancement to facilitate true engineering of synthetic microbial metabolism.
American Psychological Association (APA)
McArthur, George H.& Fong, Stephen S.. 2009. Toward Engineering Synthetic Microbial Metabolism. BioMed Research International،Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-988922
Modern Language Association (MLA)
McArthur, George H.& Fong, Stephen S.. Toward Engineering Synthetic Microbial Metabolism. BioMed Research International No. 2010 (Dec. 2010), pp.1-10.
https://search.emarefa.net/detail/BIM-988922
American Medical Association (AMA)
McArthur, George H.& Fong, Stephen S.. Toward Engineering Synthetic Microbial Metabolism. BioMed Research International. 2009. Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-988922
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988922