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What We Know and Do Not Know about Sex and Cardiac Disease
Author
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-30
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Cardiovascular disease (CVD) remains the single leading cause of death in both men and women.
A large proportion of the population with CVD will die with a diagnosis of congestive heart failure (CHF).
It is becoming increasingly recognized that sex differences exist in the etiology, development, and outcome of CHF.
For example, compared to male counterparts, women that present with CHF are typically older and have systolic cardiac function that is not impaired.
Despite a growing body of literature addressing the underlying mechanisms of sex dimorphisms in cardiac disease, there remain significant inconsistencies reported in these studies.
Given that the development of CHF results from the complex integration of genetic and nongenetic cues, it is not surprising that the elucidation and subsequent identification of molecular mechanisms remains unclear.
In this review, key aspects of sex differences in CVD and CHF will be highlighted with an emphasis on some of the unanswered questions regarding these differences.
The contention is presented that it becomes critical to reference cellular mechanisms within the context of each sex to better understand these sex dimorphisms.
American Psychological Association (APA)
Konhilas, John P.. 2010. What We Know and Do Not Know about Sex and Cardiac Disease. BioMed Research International،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-988991
Modern Language Association (MLA)
Konhilas, John P.. What We Know and Do Not Know about Sex and Cardiac Disease. BioMed Research International No. 2010 (Dec. 2010), pp.1-11.
https://search.emarefa.net/detail/BIM-988991
American Medical Association (AMA)
Konhilas, John P.. What We Know and Do Not Know about Sex and Cardiac Disease. BioMed Research International. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-988991
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-988991