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Regulation of Gene Expression in Protozoa Parasites
Joint Authors
Rodríguez, Mario A.
Esther Ramirez, M.
Gomez, Consuelo
Flores, Maria Olivia Medel
Calixto-Galvez, Mercedes
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-24, 24 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-09
Country of Publication
Egypt
No. of Pages
24
Main Subjects
Abstract EN
Infections with protozoa parasites are associated with high burdens of morbidity and mortality across the developing world.
Despite extensive efforts to control the transmission of these parasites, the spread of populations resistant to drugs and the lack of effective vaccines against them contribute to their persistence as major public health problems.
Parasites should perform a strict control on the expression of genes involved in their pathogenicity, differentiation, immune evasion, or drug resistance, and the comprehension of the mechanisms implicated in that control could help to develop novel therapeutic strategies.
However, until now these mechanisms are poorly understood in protozoa.
Recent investigations into gene expression in protozoa parasites suggest that they possess many of the canonical machineries employed by higher eukaryotes for the control of gene expression at transcriptional, posttranscriptional, and epigenetic levels, but they also contain exclusive mechanisms.
Here, we review the current understanding about the regulation of gene expression in Plasmodium sp., Trypanosomatids, Entamoeba histolytica and Trichomonas vaginalis.
American Psychological Association (APA)
Gomez, Consuelo& Esther Ramirez, M.& Calixto-Galvez, Mercedes& Flores, Maria Olivia Medel& Rodríguez, Mario A.. 2010. Regulation of Gene Expression in Protozoa Parasites. BioMed Research International،Vol. 2010, no. 2010, pp.1-24.
https://search.emarefa.net/detail/BIM-989091
Modern Language Association (MLA)
Gomez, Consuelo…[et al.]. Regulation of Gene Expression in Protozoa Parasites. BioMed Research International No. 2010 (Dec. 2010), pp.1-24.
https://search.emarefa.net/detail/BIM-989091
American Medical Association (AMA)
Gomez, Consuelo& Esther Ramirez, M.& Calixto-Galvez, Mercedes& Flores, Maria Olivia Medel& Rodríguez, Mario A.. Regulation of Gene Expression in Protozoa Parasites. BioMed Research International. 2010. Vol. 2010, no. 2010, pp.1-24.
https://search.emarefa.net/detail/BIM-989091
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989091