A Novel Negative Fe-Deficiency-Responsive Element and a TGGCA-Type-Like FeRE Control the Expression of FTR1 in Chlamydomonas reinhardtii

Joint Authors

Eriksson, Mats
Fei, Xiaowen
Deng, Xiaodong
Li, Yajun

Source

BioMed Research International

Issue

Vol. 2010, Issue 2010 (31 Dec. 2009), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-01-31

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Medicine

Abstract EN

We have reported three Fe-deficiency-responsive elements (FEREs), FOX1, ATX1, and FEA1, all of which are positive regulatory elements in response to iron deficiency in Chlamydomonas reinhardtii.

Here we describe FTR1, another iron regulated gene and mutational analysis of its promoter.

Our results reveal that the FeREs of FTR1 distinguish itself from other iron response elements by containing both negative and positive regulatory regions.

In FTR1, the −291/−236 region from the transcriptional start site is necessary and sufficient for Fe-deficiency-inducible expression.

This region contains two positive FeREs with a TGGCA-like core sequence: the FtrFeRE1 (ATGCAGGCT) at −287/−279 and the FtrFeRE2 (AAGCGATTGCCAGAGCGC) at −253/−236.

Furthermore, we identified a novel FERE, FtrFeRE3 (AGTAACTGTTAAGCC) localized at −319/−292, which negatively influences the expression of FTR1.

American Psychological Association (APA)

Fei, Xiaowen& Eriksson, Mats& Li, Yajun& Deng, Xiaodong. 2010. A Novel Negative Fe-Deficiency-Responsive Element and a TGGCA-Type-Like FeRE Control the Expression of FTR1 in Chlamydomonas reinhardtii. BioMed Research International،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-989121

Modern Language Association (MLA)

Fei, Xiaowen…[et al.]. A Novel Negative Fe-Deficiency-Responsive Element and a TGGCA-Type-Like FeRE Control the Expression of FTR1 in Chlamydomonas reinhardtii. BioMed Research International No. 2010 (Dec. 2010), pp.1-9.
https://search.emarefa.net/detail/BIM-989121

American Medical Association (AMA)

Fei, Xiaowen& Eriksson, Mats& Li, Yajun& Deng, Xiaodong. A Novel Negative Fe-Deficiency-Responsive Element and a TGGCA-Type-Like FeRE Control the Expression of FTR1 in Chlamydomonas reinhardtii. BioMed Research International. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-989121

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-989121