Genome-Wide Identification and Analysis of the Chicken Basic Helix-Loop-Helix Factors
Joint Authors
Source
International Journal of Genomics
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-04-11
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Members of the basic helix-loop-helix (bHLH) family of transcription factors play important roles in a wide range of developmental processes.
In this study, we conducted a genome-wide survey using the chicken (Gallus gallus) genomic database, and identified 104 bHLH sequences belonging to 42 gene families in an effort to characterize the chicken bHLH transcription factor family.
Phylogenetic analyses revealed that chicken has 50, 21, 15, 4, 8, and 3 bHLH members in groups A, B, C, D, E, and F, respectively, while three members belonging to none of these groups were classified as ‘‘orphans’’.
A comparison between chicken and human bHLH repertoires suggested that both organisms have a number of lineage-specific bHLH members in the proteomes.
Chromosome distribution patterns and phylogenetic analyses strongly suggest that the bHLH members should have arisen through gene duplication at an early date.
Gene Ontology (GO) enrichment statistics showed 51 top GO annotations of biological processes counted in the frequency.
The present study deepens our understanding of the chicken bHLH transcription factor family and provides much useful information for further studies using chicken as a model system.
American Psychological Association (APA)
Liu, Wu-yi& Zhao, Chun-jiang. 2010. Genome-Wide Identification and Analysis of the Chicken Basic Helix-Loop-Helix Factors. International Journal of Genomics،Vol. 2010, no. 2010, pp.1-12.
https://search.emarefa.net/detail/BIM-989235
Modern Language Association (MLA)
Liu, Wu-yi& Zhao, Chun-jiang. Genome-Wide Identification and Analysis of the Chicken Basic Helix-Loop-Helix Factors. International Journal of Genomics No. 2010 (2010), pp.1-12.
https://search.emarefa.net/detail/BIM-989235
American Medical Association (AMA)
Liu, Wu-yi& Zhao, Chun-jiang. Genome-Wide Identification and Analysis of the Chicken Basic Helix-Loop-Helix Factors. International Journal of Genomics. 2010. Vol. 2010, no. 2010, pp.1-12.
https://search.emarefa.net/detail/BIM-989235
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989235