New Automated and High-Throughput Quantitative Analysis of Urinary Ketones by Multifiber Exchange-Solid Phase Microextraction Coupled to Fast Gas ChromatographyNegative Chemical-Electron IonizationMass Spectrometry
Joint Authors
Franchi, Elena
Cupelli, Vincenzo
Alessi, Paolo
Bonacchi, Alice
Arcangeli, Giulio
Kikic, Ireneo
Calamante, Massimo
Pacenti, Marco
Perchiazzi, Nicola
Degli Esposti, Filippo
Traldi, Pietro
Salvadori, Edoardo
Dugheri, Stefano
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-18
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The present research is focused on automation, miniaturization, and system interaction with high throughput for multiple and specific Direct Immersion-Solid Phase Microextraction/Fast Gas Chromatography analysis of the urinary ketones.
The specific Mass Spectrometry instrumentation, capable of supporting such the automated changeover from Negative Chemical to Electron Ionization mode, as well as the automation of the preparation procedure by new device called MultiFiber Exchange, through change of the fibers, allowed a friendly use of mass spectrometry apparatus with a number of advantages including reduced analyst time and greater reproducibility (2.01–5.32%).
The detection limits for the seven ketones were less than 0.004 mg/L.
For an innovative powerful meaning in high-throughput routine, the generality of the structurally informative Mass Spectrometry fragmentation patterns together with the chromatographic separation and software automation are also investigated.
American Psychological Association (APA)
Pacenti, Marco& Dugheri, Stefano& Traldi, Pietro& Degli Esposti, Filippo& Perchiazzi, Nicola& Franchi, Elena…[et al.]. 2010. New Automated and High-Throughput Quantitative Analysis of Urinary Ketones by Multifiber Exchange-Solid Phase Microextraction Coupled to Fast Gas ChromatographyNegative Chemical-Electron IonizationMass Spectrometry. Journal of Analytical Methods in Chemistry،Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-989245
Modern Language Association (MLA)
Pacenti, Marco…[et al.]. New Automated and High-Throughput Quantitative Analysis of Urinary Ketones by Multifiber Exchange-Solid Phase Microextraction Coupled to Fast Gas ChromatographyNegative Chemical-Electron IonizationMass Spectrometry. Journal of Analytical Methods in Chemistry No. 2010 (2010), pp.1-13.
https://search.emarefa.net/detail/BIM-989245
American Medical Association (AMA)
Pacenti, Marco& Dugheri, Stefano& Traldi, Pietro& Degli Esposti, Filippo& Perchiazzi, Nicola& Franchi, Elena…[et al.]. New Automated and High-Throughput Quantitative Analysis of Urinary Ketones by Multifiber Exchange-Solid Phase Microextraction Coupled to Fast Gas ChromatographyNegative Chemical-Electron IonizationMass Spectrometry. Journal of Analytical Methods in Chemistry. 2010. Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-989245
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989245