DNA Vaccination: Using the Patient's Immune System to Overcome Cancer
Joint Authors
Lode, Holger N.
Preissner, Robert
Eschenburg, Georg
Meyer, Hellmuth-Alexander
Stermann, Alexander
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-24
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Cancer is one of the most challenging diseases of today.
Optimization of standard treatment protocols consisting of the main columns of chemo- and radiotherapy followed or preceded by surgical intervention is often limited by toxic side effects and induction of concomitant malignancies and/or development of resistant mechanisms.
This requires the development of therapeutic strategies which are as effective as standard therapies but permit the patients a life without severe negative side effects.
Along this line, the development of immunotherapy in general and the innovative concept of DNA vaccination in particular may provide a venue to achieve this goal.
Using the patient's own immune system by activation of humoral and cellular immune responses to target the cancer cells has shown first promising results in clinical trials and may allow reduced toxicity standard therapy regimen in the future.
The main challenge of this concept is to transfer the plethora of convincing preclinical and early clinical results to an effective treatment of patients.
American Psychological Association (APA)
Eschenburg, Georg& Stermann, Alexander& Preissner, Robert& Meyer, Hellmuth-Alexander& Lode, Holger N.. 2010. DNA Vaccination: Using the Patient's Immune System to Overcome Cancer. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-14.
https://search.emarefa.net/detail/BIM-989288
Modern Language Association (MLA)
Eschenburg, Georg…[et al.]. DNA Vaccination: Using the Patient's Immune System to Overcome Cancer. Journal of Immunology Research No. 2010 (2010), pp.1-14.
https://search.emarefa.net/detail/BIM-989288
American Medical Association (AMA)
Eschenburg, Georg& Stermann, Alexander& Preissner, Robert& Meyer, Hellmuth-Alexander& Lode, Holger N.. DNA Vaccination: Using the Patient's Immune System to Overcome Cancer. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-14.
https://search.emarefa.net/detail/BIM-989288
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989288