Developmental Profiles of Mucosal Immunity in Pre-school Children
Joint Authors
Cripps, Allan W.
Occhipinti, Stefano
Otczyk, Diana C.
Gleeson, Maree
Ewing, Patricia
Kyd, Jennelle M.
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
This study investigated the effect of attending pre-school on mucosal immunity.
Children 3.5 to 5 years of age who attended pre-school were observed for a 10 month period.
Demographic information was collected on previous childcare experiences, the home environment and clinical information relating to the child and the family.
A daily illness log was kept for each child.
A multivariate longitudinal analysis of the relation between immunoglobulins in saliva and age, gender, childcare experience, pre-school exposure, number of siblings, environmental tobacco smoke (ETS), atopy and hospitalisation was conducted.
There was a positive association of higher IgA levels with the winter season and with children being older than 4 years (P<.001), having attended childcare prior to commencing pre-school (P<.05), and having been exposed to ETS at home (P<.05).
Lower IgA levels were associated with being atopic (P<.05).
Higher IgG levels were associated with exposure to ETS (P<.001), while lower levels were associated to having atopy.
Higher IgM levels were associated with previous childcare experience (P<.01) whilst having been hospitalised was associated with having low salivary IgM levels (P<.01).
Lagged analyses demonstrated that immunological parameters were affected by the number of respiratory infections in the preceding 2 months.
American Psychological Association (APA)
Ewing, Patricia& Otczyk, Diana C.& Occhipinti, Stefano& Kyd, Jennelle M.& Gleeson, Maree& Cripps, Allan W.. 2010. Developmental Profiles of Mucosal Immunity in Pre-school Children. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-989291
Modern Language Association (MLA)
Ewing, Patricia…[et al.]. Developmental Profiles of Mucosal Immunity in Pre-school Children. Journal of Immunology Research No. 2010 (2010), pp.1-10.
https://search.emarefa.net/detail/BIM-989291
American Medical Association (AMA)
Ewing, Patricia& Otczyk, Diana C.& Occhipinti, Stefano& Kyd, Jennelle M.& Gleeson, Maree& Cripps, Allan W.. Developmental Profiles of Mucosal Immunity in Pre-school Children. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-989291
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989291