Theoretical Modeling Techniques and Their Impact on Tumor Immunology
Joint Authors
Preissner, Robert
Murgueitio, Manuela S.
Woelke, Anna Lena
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Currently, cancer is one of the leading causes of death in industrial nations.
While conventional cancer treatment usually results in the patient suffering from severe side effects, immunotherapy is a promising alternative.
Nevertheless, some questions remain unanswered with regard to using immunotherapy to treat cancer hindering it from being widely established.
To help rectify this deficit in knowledge, experimental data, accumulated from a huge number of different studies, can be integrated into theoretical models of the tumor-immune system interaction.
Many complex mechanisms in immunology and oncology cannot be measured in experiments, but can be analyzed by mathematical simulations.
Using theoretical modeling techniques, general principles of tumor-immune system interactions can be explored and clinical treatment schedules optimized to lower both tumor burden and side effects.
In this paper, we aim to explain the main mathematical and computational modeling techniques used in tumor immunology to experimental researchers and clinicians.
In addition, we review relevant published work and provide an overview of its impact to the field.
American Psychological Association (APA)
Woelke, Anna Lena& Murgueitio, Manuela S.& Preissner, Robert. 2010. Theoretical Modeling Techniques and Their Impact on Tumor Immunology. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-989296
Modern Language Association (MLA)
Woelke, Anna Lena…[et al.]. Theoretical Modeling Techniques and Their Impact on Tumor Immunology. Journal of Immunology Research No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-989296
American Medical Association (AMA)
Woelke, Anna Lena& Murgueitio, Manuela S.& Preissner, Robert. Theoretical Modeling Techniques and Their Impact on Tumor Immunology. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-989296
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989296