Hyper-IgE Syndrome with STAT3 Mutation: A Case Report in Mainland China
Joint Authors
Zhang, Weihua
Chen, Liang'an
Xie, Lixin
Hu, Xiaoxiang
Li, Yang
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Hyper-immunoglobulin E syndromes (HIES) including compound primary immunodeficiency and nonimmunological abnormalities are characterized by extremely high serum IgE levels, eosinophilia, eczema, susceptibility to infections, distinctive facial appearance, retention of deciduous teeth, cyst-forming pneumonias, and skeletal abnormalities.
Itis reported that some cases of familial HIES are relative to autosomal dominant or recessive inheritance, but most cases are sporadic, and result from mutations in the human signal transducer and activator of transcription 3 (STAT3) gene.
In this paper, we firstly report a young man diagnosed of Hyper-IgE syndrome with STAT3 mutation in Mainland China, and investigate the autosomal dominant trait of his family members.
American Psychological Association (APA)
Xie, Lixin& Hu, Xiaoxiang& Li, Yang& Zhang, Weihua& Chen, Liang'an. 2010. Hyper-IgE Syndrome with STAT3 Mutation: A Case Report in Mainland China. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-989298
Modern Language Association (MLA)
Xie, Lixin…[et al.]. Hyper-IgE Syndrome with STAT3 Mutation: A Case Report in Mainland China. Journal of Immunology Research No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-989298
American Medical Association (AMA)
Xie, Lixin& Hu, Xiaoxiang& Li, Yang& Zhang, Weihua& Chen, Liang'an. Hyper-IgE Syndrome with STAT3 Mutation: A Case Report in Mainland China. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-989298
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989298