Mycobacterium bovis Bacillus Calmette-Guérin-Induced Macrophage Cytotoxicity against Bladder Cancer Cells
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Many details of the molecular and cellular mechanisms involved in Mycobacterium bovis bacillus Calmette-Guérin (BCG) immunotherapy of bladder cancer have been discovered in the past decades.
However, information on a potential role for macrophage cytotoxicity as an effector mechanism is limited.
Macrophages play pivotal roles in the host innate immunity and serve as a first line of defense in mycobacterial infection.
In addition to their function as professional antigen-presenting cells, the tumoricidal activity of macrophages has also been studied with considerable interest.
Studies have shown that activated macrophages are potent in killing malignant cells of various tissue origins.
This review summarizes the current understanding of the BCG-induced macrophage cytotoxicity toward bladder cancer cells with an intention to inspire investigation on this important but underdeveloped research field.
American Psychological Association (APA)
Luo, Yi& Knudson, Matthew J.. 2010. Mycobacterium bovis Bacillus Calmette-Guérin-Induced Macrophage Cytotoxicity against Bladder Cancer Cells. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-989304
Modern Language Association (MLA)
Luo, Yi& Knudson, Matthew J.. Mycobacterium bovis Bacillus Calmette-Guérin-Induced Macrophage Cytotoxicity against Bladder Cancer Cells. Journal of Immunology Research No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-989304
American Medical Association (AMA)
Luo, Yi& Knudson, Matthew J.. Mycobacterium bovis Bacillus Calmette-Guérin-Induced Macrophage Cytotoxicity against Bladder Cancer Cells. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-989304
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989304