B7-H3 and Its Role in Antitumor Immunity
Joint Authors
Loos, Martin
Friess, Helmut
Hedderich, Dennis M.
Kleeff, Jorg
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
B7-H3 is one of the most recently identified members of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T-cell response.
Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.
However, its precise physiologic role is still elusive, because both stimulatory and inhibitory capacities have been demonstrated.
This paper summarizes the available data on B7-H3 in the regulation of T-cell response focusing on its potential role in antitumor immunity.
American Psychological Association (APA)
Loos, Martin& Hedderich, Dennis M.& Friess, Helmut& Kleeff, Jorg. 2010. B7-H3 and Its Role in Antitumor Immunity. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-989328
Modern Language Association (MLA)
Loos, Martin…[et al.]. B7-H3 and Its Role in Antitumor Immunity. Journal of Immunology Research No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-989328
American Medical Association (AMA)
Loos, Martin& Hedderich, Dennis M.& Friess, Helmut& Kleeff, Jorg. B7-H3 and Its Role in Antitumor Immunity. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-989328
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989328
