Overview of Cellular Immunotherapy for Patients with Glioblastoma
Joint Authors
Avril, Tony
Mosser, Jean
Collet, Brigitte
Vauléon, Elodie
Quillien, Véronique
Source
Journal of Immunology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-31
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
High grade gliomas (HGG) including glioblastomas (GBM) are the most common and devastating primary brain tumours.
Despite important progresses in GBM treatment that currently includes surgery combined to radio- and chemotherapy, GBM patients' prognosis remains very poor.
Immunotherapy is one of the new promising therapeutic approaches that can specifically target tumour cells.
Such an approach could also maintain long term antitumour responses without inducing neurologic defects.
Since the past 25 years, adoptive and active immunotherapies using lymphokine-activated killer cells, cytotoxic T cells, tumour-infiltrating lymphocytes, autologous tumour cells, and dendritic cells have been tested in phase I/II clinical trials with HGG patients.
This paper inventories these cellular immunotherapeutic strategies and discusses their efficacy, limits, and future perspectives for optimizing the treatment to achieve clinical benefits for GBM patients.
American Psychological Association (APA)
Vauléon, Elodie& Avril, Tony& Collet, Brigitte& Mosser, Jean& Quillien, Véronique. 2010. Overview of Cellular Immunotherapy for Patients with Glioblastoma. Journal of Immunology Research،Vol. 2010, no. 2010, pp.1-18.
https://search.emarefa.net/detail/BIM-989329
Modern Language Association (MLA)
Vauléon, Elodie…[et al.]. Overview of Cellular Immunotherapy for Patients with Glioblastoma. Journal of Immunology Research No. 2010 (2010), pp.1-18.
https://search.emarefa.net/detail/BIM-989329
American Medical Association (AMA)
Vauléon, Elodie& Avril, Tony& Collet, Brigitte& Mosser, Jean& Quillien, Véronique. Overview of Cellular Immunotherapy for Patients with Glioblastoma. Journal of Immunology Research. 2010. Vol. 2010, no. 2010, pp.1-18.
https://search.emarefa.net/detail/BIM-989329
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989329