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Radiation Therapy for Palliation of Sarcoma Metastases: A Unique and Uniform Hypofractionation Experience
Joint Authors
Tempelhoff, Haim
Kollender, Yehuda
Merimsky, Ofer
Soyfer, Viacheslav
Corn, Benjamin W.
Meller, Isaac
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-22
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Radiotherapy (RT) is our preferred modality for local palliation of metastatic soft tissue sarcoma (STS).
A short and intense course of RT is usually needed for rapid palliation and local control of metastatic disease.
Seventeen patients at a median age of 61 had symptomatic metastatic sarcoma and required rapid palliation.
The symptoms related to the metastases were either pain or discomfort.
All patients were treated by a short and intensive course of administration: 39 Gy were given in 13 fractions of 3 Gy/day, 5 times a week.
Median follow-up period was 25 weeks.
The treatment was well tolerated.
Acute side effects included grade one skin toxicity.
No wound complications were noted among those undergoing surgery.
Late side effects included skin pigmentation and induration of irradiated soft tissues.
Durable pain control was achieved in 12 out 15 cases treated for gross metastases.
Tumor progression was seen in the 3 other cases within a period of two to nine months.
Among 5 lesions which were irradiated as an adjunctive treatment following resection, no local recurrence was observed.
The results of this series, although limited in size, point to the safety and feasibility of hypofractionated RT for palliation of musculoskeletal metastases from sarcoma
American Psychological Association (APA)
Soyfer, Viacheslav& Corn, Benjamin W.& Kollender, Yehuda& Tempelhoff, Haim& Meller, Isaac& Merimsky, Ofer. 2010. Radiation Therapy for Palliation of Sarcoma Metastases: A Unique and Uniform Hypofractionation Experience. Complexity،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-989744
Modern Language Association (MLA)
Soyfer, Viacheslav…[et al.]. Radiation Therapy for Palliation of Sarcoma Metastases: A Unique and Uniform Hypofractionation Experience. Complexity No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-989744
American Medical Association (AMA)
Soyfer, Viacheslav& Corn, Benjamin W.& Kollender, Yehuda& Tempelhoff, Haim& Meller, Isaac& Merimsky, Ofer. Radiation Therapy for Palliation of Sarcoma Metastases: A Unique and Uniform Hypofractionation Experience. Complexity. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-989744
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989744