Toxicokinetics of Kava
Joint Authors
Ramzan, Iqbal
Zhang, Lillian Yuan
Rowe, Anthony
Source
Advances in Pharmacological and Pharmaceutical Sciences
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Kava is traditionally consumed by South Pacific islanders as a drink and became popular in Western society as a supplement for anxiety and insomnia.
Kava extracts are generally well tolerated, but reports of hepatotoxicity necessitated an international reappraisal of its safety.
Hepatotoxicity can occur as an acute, severe form or a chronic, mild form.
Inflammation appears to be involved in both forms and may result from activation of liver macrophages (Kupffer cells), either directly or via kava metabolites.
Pharmacogenomics may influence the severity of this inflammatory response.
American Psychological Association (APA)
Rowe, Anthony& Zhang, Lillian Yuan& Ramzan, Iqbal. 2011. Toxicokinetics of Kava. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-989845
Modern Language Association (MLA)
Rowe, Anthony…[et al.]. Toxicokinetics of Kava. Advances in Pharmacological and Pharmaceutical Sciences No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-989845
American Medical Association (AMA)
Rowe, Anthony& Zhang, Lillian Yuan& Ramzan, Iqbal. Toxicokinetics of Kava. Advances in Pharmacological and Pharmaceutical Sciences. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-989845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989845
