Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates
Joint Authors
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-11-30
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Acetylation of lysines is a prominent form of modification in mammalian proteins.
Deacetylation of proteins is catalyzed by histone deacetylases, traditionally named after their role in histone deacetylation, transcriptional modulation, and epigenetic regulation.
Despite the link between histone deacetylases and chromatin structure, some of the histone deacetylases reside in various compartments in the cytoplasm.
Here, we review how these cytoplasmic histone deacetylases are regulated, the identification of nonhistone substrates, and the functional implications of their nondeacetylase enzymatic activities.
American Psychological Association (APA)
Yao, Ya-Li& Yang, Wen-Ming. 2010. Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates. BioMed Research International،Vol. 2011, no. 2011, pp.1-15.
https://search.emarefa.net/detail/BIM-989875
Modern Language Association (MLA)
Yao, Ya-Li& Yang, Wen-Ming. Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates. BioMed Research International No. 2011 (2011), pp.1-15.
https://search.emarefa.net/detail/BIM-989875
American Medical Association (AMA)
Yao, Ya-Li& Yang, Wen-Ming. Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates. BioMed Research International. 2010. Vol. 2011, no. 2011, pp.1-15.
https://search.emarefa.net/detail/BIM-989875
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989875