Ion Transport by Pulmonary Epithelia
Joint Authors
Richter, Katrin
Hollenhorst, Monika I.
Fronius, Martin
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-27
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
The lung surface of air-breathing vertebrates is formed by a continuous epithelium that is covered by a fluid layer.
In the airways, this epithelium is largely pseudostratified consisting of diverse cell types such as ciliated cells, goblet cells, and undifferentiated basal cells, whereas the alveolar epithelium consists of alveolar type I and alveolar type II cells.
Regulation and maintenance of the volume and viscosity of the fluid layer covering the epithelium is one of the most important functions of the epithelial barrier that forms the outer surface area of the lungs.
Therefore, the epithelial cells are equipped with a wide variety of ion transport proteins, among which Na+, Cl−, and K+ channels have been identified to play a role in the regulation of the fluid layer.
Malfunctions of pulmonary epithelial ion transport processes and, thus, impairment of the liquid balance in our lungs is associated with severe diseases, such as cystic fibrosis and pulmonary oedema.
Due to the important role of pulmonary epithelial ion transport processes for proper lung function, the present paper summarizes the recent findings about composition, function, and ion transport properties of the airway epithelium as well as of the alveolar epithelium.
American Psychological Association (APA)
Hollenhorst, Monika I.& Richter, Katrin& Fronius, Martin. 2011. Ion Transport by Pulmonary Epithelia. BioMed Research International،Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-989889
Modern Language Association (MLA)
Hollenhorst, Monika I.…[et al.]. Ion Transport by Pulmonary Epithelia. BioMed Research International No. 2011 (2011), pp.1-16.
https://search.emarefa.net/detail/BIM-989889
American Medical Association (AMA)
Hollenhorst, Monika I.& Richter, Katrin& Fronius, Martin. Ion Transport by Pulmonary Epithelia. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-989889
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989889