Diagnostic Value of I-131 NP-59 SPECTCT Scintigraphy in Patients with Subclinical or Atypical Features of Primary Aldosteronism
Joint Authors
Tseng, Chih-En
Chiu, Jainn-Shiun
Su, Yu-Chieh
Chen, Shao-Jer
Chen, Yi-Chun
Wei, Chang-Kuo
Wang, Yuh-Feng
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Accumulating evidence has shown the adverse effect of long-term hyperaldosteronism on cardiovascular morbidity that is independent of blood pressure.
However, the diagnosis of primary aldosteronism (PA) remains a challenge for patients who present with subtle or atypical features or have chronic kidney disease (CKD).
SPECT/CT has proven valuable in the diagnosis of a number of conditions.
The aim of this study was to determine the usefulness of I-131 NP-59 SPECT/CT in patients with atypical presentations of PA and in those with CKD.
The records of 15 patients with PA were retrospectively analyzed.
NP-59 SPECT/CT was able to identify adrenal lesion(s) in CKD patients with suspected PA.
Patients using NP-59 SPECT/CT imaging, compared with those not performing this procedure, significantly featured nearly normal serum potassium levels, normal aldosterone-renin ratio, and smaller adrenal size on CT and pathological examination and tended to feature stage 1 hypertension and non-suppressed plasma renin activity.
These findings show that noninvasive NP-59 SPECT/CT is a useful tool for diagnosis in patients with subclinical or atypical features of PA and those with CKD.
American Psychological Association (APA)
Chen, Yi-Chun& Su, Yu-Chieh& Wei, Chang-Kuo& Chiu, Jainn-Shiun& Tseng, Chih-En& Chen, Shao-Jer…[et al.]. 2011. Diagnostic Value of I-131 NP-59 SPECTCT Scintigraphy in Patients with Subclinical or Atypical Features of Primary Aldosteronism. BioMed Research International،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-989927
Modern Language Association (MLA)
Chen, Yi-Chun…[et al.]. Diagnostic Value of I-131 NP-59 SPECTCT Scintigraphy in Patients with Subclinical or Atypical Features of Primary Aldosteronism. BioMed Research International No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-989927
American Medical Association (AMA)
Chen, Yi-Chun& Su, Yu-Chieh& Wei, Chang-Kuo& Chiu, Jainn-Shiun& Tseng, Chih-En& Chen, Shao-Jer…[et al.]. Diagnostic Value of I-131 NP-59 SPECTCT Scintigraphy in Patients with Subclinical or Atypical Features of Primary Aldosteronism. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-989927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989927