Motor-Evoked Potential Confirmation of Functional Improvement by Transplanted Bone Marrow Mesenchymal Stem Cell in the Ischemic Rat Brain
Joint Authors
Maeng, Lee-So
Jung, Seong-Whan
Kim, Min-Wook
Yoo, Do-Sung
Park, Moon-Seo
Chung, Young-An
Huh, Pil-Woo
Jang, Kyung-Sool
Han, Young-Min
Park, Sang-In
Jang, Dong-Kyu
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-09
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
This study investigated the effect of bone marrow mesenchymal stem cells (BMSCs) on the motor pathway in the transient ischemic rat brain that were transplanted through the carotid artery, measuring motor-evoked potential (MEP) in the four limbs muscle and the atlantooccipital membrane, which was elicited after monopolar and bipolar transcortical stimulation.
After monopolar stimulation, the latency of MEP was significantly prolonged, and the amplitude was less reduced in the BMSC group in comparison with the control group (P<.05).
MEPs induced by bipolar stimulation in the left forelimb could be measured in 40% of the BMSC group and the I wave that was not detected in the control group was also detected in 40% of the BMSC group.
Our preliminary results imply that BMSCs transplanted to the ischemic rat brain mediate effects on the functional recovery of the cerebral motor cortex and the motor pathway.
American Psychological Association (APA)
Jang, Dong-Kyu& Park, Sang-In& Han, Young-Min& Jang, Kyung-Sool& Park, Moon-Seo& Chung, Young-An…[et al.]. 2011. Motor-Evoked Potential Confirmation of Functional Improvement by Transplanted Bone Marrow Mesenchymal Stem Cell in the Ischemic Rat Brain. BioMed Research International،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-989943
Modern Language Association (MLA)
Jang, Dong-Kyu…[et al.]. Motor-Evoked Potential Confirmation of Functional Improvement by Transplanted Bone Marrow Mesenchymal Stem Cell in the Ischemic Rat Brain. BioMed Research International No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-989943
American Medical Association (AMA)
Jang, Dong-Kyu& Park, Sang-In& Han, Young-Min& Jang, Kyung-Sool& Park, Moon-Seo& Chung, Young-An…[et al.]. Motor-Evoked Potential Confirmation of Functional Improvement by Transplanted Bone Marrow Mesenchymal Stem Cell in the Ischemic Rat Brain. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-989943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989943