TP53 Status and Response to Treatment in Breast Cancers
Joint Authors
Bertheau, Philippe
Plassa, Louis-François
Bousquet, Guilhem
Janin, Anne
Varna, Mariana
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The p53 wild-type protein plays an important role in cells as is shown by its fine regulation at different levels.
Since its discovery, numerous mutations have been described.
In breast cancers, p53 is mutated in almost 30% of cases, with a higher frequency in some tumor subtypes.
TP53 mutation is reported to be a factor for good prognosis in some studies, while in others it is a factor for poor prognosis.
The explanation for these different results could be linked to the fact that the studies were performed on different tumor types and with different therapy regimens.
American Psychological Association (APA)
Varna, Mariana& Bousquet, Guilhem& Plassa, Louis-François& Bertheau, Philippe& Janin, Anne. 2011. TP53 Status and Response to Treatment in Breast Cancers. BioMed Research International،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-989978
Modern Language Association (MLA)
Varna, Mariana…[et al.]. TP53 Status and Response to Treatment in Breast Cancers. BioMed Research International No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-989978
American Medical Association (AMA)
Varna, Mariana& Bousquet, Guilhem& Plassa, Louis-François& Bertheau, Philippe& Janin, Anne. TP53 Status and Response to Treatment in Breast Cancers. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-989978
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989978