Consumption of Hydrogen Water Reduces Paraquat-Induced Acute Lung Injury in Rats
Joint Authors
Liu, Kan
Liu, Wenwu
Tao, Hengyi
Xu, Weigang
Denoble, Petar
Sun, Xuejun
Sun, Qiang
Liu, Shulin
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Exposure to paraquat leads to acute lung injury and oxidative stress is widely accepted as a contributor to paraquat-induced acute lung injury.
Recent studies have reported that consumption of water with dissolved molecular hydrogen to a saturated level (hydrogen water) prevents oxidative stress-induced diseases.
Here, we investigated whether consumption of saturated hydrogen saline protects rats against paraquat-induced acute lung injury.
Adult male Sprague-Dawley (SD) rats were randomly divided into four groups: Control group; hydrogen water-only group (HW group); paraquat-only group (PQ group); paraquat and hydrogen water group (PQ + HW group).
The rats in control group and HW group drank pure water or hydrogen water; the rats in PQ group and PQ + HW group were intraperitonealy injected with paraquat (35 mg/kg) and then provided pure water or hydrogen water.
Both biochemical and histological lung alterations were measured.
The results showed that hydrogen water ameliorated these alterations, demonstrating that hydrogen water alleviated paraquat-induced acute lung injury possibly by inhibition of oxidative damage.
American Psychological Association (APA)
Liu, Shulin& Liu, Kan& Sun, Qiang& Liu, Wenwu& Xu, Weigang& Denoble, Petar…[et al.]. 2011. Consumption of Hydrogen Water Reduces Paraquat-Induced Acute Lung Injury in Rats. BioMed Research International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-989999
Modern Language Association (MLA)
Liu, Shulin…[et al.]. Consumption of Hydrogen Water Reduces Paraquat-Induced Acute Lung Injury in Rats. BioMed Research International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-989999
American Medical Association (AMA)
Liu, Shulin& Liu, Kan& Sun, Qiang& Liu, Wenwu& Xu, Weigang& Denoble, Petar…[et al.]. Consumption of Hydrogen Water Reduces Paraquat-Induced Acute Lung Injury in Rats. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-989999
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-989999